MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS
The new rapid molecular genotyping method was developed for studying the structure of ptxP promoter of pertussis toxin. Method is based on PCR-RFLP analysis, which allows studying the specific restriction profiles of the B. pertussis strains and allows differentiation of the strains with the ptxP st...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Diagnostics and Vaccines"
2015-08-01
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| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/113 |
| _version_ | 1797881876012072960 |
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| author | G. A. Ivashinnikova O. U. Borisova A. V. Aleshkin A. S. Pimenova V. A. Aleshkin |
| author_facet | G. A. Ivashinnikova O. U. Borisova A. V. Aleshkin A. S. Pimenova V. A. Aleshkin |
| author_sort | G. A. Ivashinnikova |
| collection | DOAJ |
| description | The new rapid molecular genotyping method was developed for studying the structure of ptxP promoter of pertussis toxin. Method is based on PCR-RFLP analysis, which allows studying the specific restriction profiles of the B. pertussis strains and allows differentiation of the strains with the ptxP structural particularities. The developed method for genotyping of strains of B. pertussis can be hhelpful when monitoring strains of the causative agent of whooping cough in system of an epidemiological surveillance over pertussis infections, allowing observation over circulating population of B.pertussis, revealing strains of the causative agent of whooping cough with high production of pertussis toxin and to watch their distribution. |
| first_indexed | 2024-04-10T03:26:00Z |
| format | Article |
| id | doaj.art-ea61dc2f936b4e5c950caed82c2d8872 |
| institution | Directory Open Access Journal |
| issn | 2072-8107 |
| language | Russian |
| last_indexed | 2024-04-10T03:26:00Z |
| publishDate | 2015-08-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj.art-ea61dc2f936b4e5c950caed82c2d88722023-03-13T07:28:22ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072015-08-01121343610.22627/2072-8107-2013-12-1-34-36113MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSISG. A. Ivashinnikova0O. U. Borisova1A. V. Aleshkin2A. S. Pimenova3V. A. Aleshkin4Московский НИИ эпидемиологии и микробиологии им. Г. Н. ГабричевскогоМосковский НИИ эпидемиологии и микробиологии им. Г. Н. ГабричевскогоМосковский НИИ эпидемиологии и микробиологии им. Г. Н. ГабричевскогоМосковский НИИ эпидемиологии и микробиологии им. Г. Н. ГабричевскогоМосковский НИИ эпидемиологии и микробиологии им. Г. Н. ГабричевскогоThe new rapid molecular genotyping method was developed for studying the structure of ptxP promoter of pertussis toxin. Method is based on PCR-RFLP analysis, which allows studying the specific restriction profiles of the B. pertussis strains and allows differentiation of the strains with the ptxP structural particularities. The developed method for genotyping of strains of B. pertussis can be hhelpful when monitoring strains of the causative agent of whooping cough in system of an epidemiological surveillance over pertussis infections, allowing observation over circulating population of B.pertussis, revealing strains of the causative agent of whooping cough with high production of pertussis toxin and to watch their distribution.https://detinf.elpub.ru/jour/article/view/113b. pertussisрестрикционный анализпромотор коклюшного токсина |
| spellingShingle | G. A. Ivashinnikova O. U. Borisova A. V. Aleshkin A. S. Pimenova V. A. Aleshkin MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS Детские инфекции (Москва) b. pertussis рестрикционный анализ промотор коклюшного токсина |
| title | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_full | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_fullStr | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_full_unstemmed | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_short | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_sort | modernization of geneotiping of strains b pertussis |
| topic | b. pertussis рестрикционный анализ промотор коклюшного токсина |
| url | https://detinf.elpub.ru/jour/article/view/113 |
| work_keys_str_mv | AT gaivashinnikova modernizationofgeneotipingofstrainsbpertussis AT ouborisova modernizationofgeneotipingofstrainsbpertussis AT avaleshkin modernizationofgeneotipingofstrainsbpertussis AT aspimenova modernizationofgeneotipingofstrainsbpertussis AT vaaleshkin modernizationofgeneotipingofstrainsbpertussis |