Understanding SCLC heterogeneity and plasticity in cancer metastasis and chemotherapy resistance

Understanding SCLC heterogeneity and plasticity in cancer metastasis and chemotherapy resistance

Small cell lung cancer (SCLC) accounts for approximately 15% of all lung cancer cases and features a strong predilection for early metastasis and extremely poor prognosis. Despite being highly sensitive to chemotherapy and/or radiotherapy initially, most SCLC patients develop therapeutic resistance...

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Bibliographic Details
Main Authors: Jin Yujuan, Chen Yanxu, Qin Zhen, Hu Liang, Guo Chenchen, Ji Hongbin
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-05-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
small cell lung cancer
heterogeneity
plasticity
metastases
chemotherapy resistance
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023080

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