Adipokines and the metabolism of key nutrients in patients with obesity

AIM: To study the effect of adipokines on the metabolism of key nutrients in patients with obesity/MATERIAL AND METHODS: Ninety patients aged 18 to 66 years old who were treated at the Department of Preventive and Rehabilitative Nutrition, Research Institute of Nutrition, Russian Academy of Medical...

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Main Authors: O O Kirillova, I V Vorozhko, K M Gapparova, Iu G Chekhonina, T B Sentsova, V A Tutel'ian
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2014-01-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/31426
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author O O Kirillova
I V Vorozhko
K M Gapparova
Iu G Chekhonina
T B Sentsova
V A Tutel'ian
author_facet O O Kirillova
I V Vorozhko
K M Gapparova
Iu G Chekhonina
T B Sentsova
V A Tutel'ian
author_sort O O Kirillova
collection DOAJ
description AIM: To study the effect of adipokines on the metabolism of key nutrients in patients with obesity/MATERIAL AND METHODS: Ninety patients aged 18 to 66 years old who were treated at the Department of Preventive and Rehabilitative Nutrition, Research Institute of Nutrition, Russian Academy of Medical Sciences, were examined. Carbohydrate and lipid metabolisms were assessed by turbidimetry and spectrophotometry. The levels of adipokines, insulin, and oxidized low-density lipoproteins (LDL) were measured by ELISA. Insulin resistance was assessed with HOMA-IR in all the patients/RESULTS: It was found that there were discoordinated changes in the content of adipokines. The patients with Grade 1 obesity, as compared to the control group, had a statistically significant decrease in the serum concentrations of adiponectin (5.94±0.90 and 15.34±0.45 µg/ml; p
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spelling doaj.art-ea62a19243a84232abc5c415851f83232022-12-22T03:47:56Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422014-01-01861454828442Adipokines and the metabolism of key nutrients in patients with obesityO O KirillovaI V VorozhkoK M GapparovaIu G ChekhoninaT B SentsovaV A Tutel'ianAIM: To study the effect of adipokines on the metabolism of key nutrients in patients with obesity/MATERIAL AND METHODS: Ninety patients aged 18 to 66 years old who were treated at the Department of Preventive and Rehabilitative Nutrition, Research Institute of Nutrition, Russian Academy of Medical Sciences, were examined. Carbohydrate and lipid metabolisms were assessed by turbidimetry and spectrophotometry. The levels of adipokines, insulin, and oxidized low-density lipoproteins (LDL) were measured by ELISA. Insulin resistance was assessed with HOMA-IR in all the patients/RESULTS: It was found that there were discoordinated changes in the content of adipokines. The patients with Grade 1 obesity, as compared to the control group, had a statistically significant decrease in the serum concentrations of adiponectin (5.94±0.90 and 15.34±0.45 µg/ml; phttps://ter-arkhiv.ru/0040-3660/article/view/31426adipokinesobesityglucoseinsulin
spellingShingle O O Kirillova
I V Vorozhko
K M Gapparova
Iu G Chekhonina
T B Sentsova
V A Tutel'ian
Adipokines and the metabolism of key nutrients in patients with obesity
Терапевтический архив
adipokines
obesity
glucose
insulin
title Adipokines and the metabolism of key nutrients in patients with obesity
title_full Adipokines and the metabolism of key nutrients in patients with obesity
title_fullStr Adipokines and the metabolism of key nutrients in patients with obesity
title_full_unstemmed Adipokines and the metabolism of key nutrients in patients with obesity
title_short Adipokines and the metabolism of key nutrients in patients with obesity
title_sort adipokines and the metabolism of key nutrients in patients with obesity
topic adipokines
obesity
glucose
insulin
url https://ter-arkhiv.ru/0040-3660/article/view/31426
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AT kmgapparova adipokinesandthemetabolismofkeynutrientsinpatientswithobesity
AT iugchekhonina adipokinesandthemetabolismofkeynutrientsinpatientswithobesity
AT tbsentsova adipokinesandthemetabolismofkeynutrientsinpatientswithobesity
AT vatutelian adipokinesandthemetabolismofkeynutrientsinpatientswithobesity