Pauson-Khand Reaction of Internal Dissymmetric Trifluoromethyl Alkynes. Influence of the Alkene on the Regioselectivity

Pauson-Khand Reaction of Internal Dissymmetric Trifluoromethyl Alkynes. Influence of the Alkene on the Regioselectivity

The scope of the Pauson-Khand reaction (PKR) of internal trifluoromethyl alkynes, previously described with norbornadiene, is expanded to norbornene and ethylene. A thorough structural analysis of the resulting PK adducts has been carried out to unveil that α-trifluoromethylcyclopentenones are prefe...

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Bibliographic Details
Main Authors:	Nuria Aiguabella, Elsa M. Arce, Carlos del Pozo, Xavier Verdaguer, Antoni Riera
Format:	Article
Language:	English
Published:	MDPI AG 2014-02-01
Series:	Molecules
Subjects:	Pauson-Khand reaction cycloadditions regioselectivity cyclopentenones trifluoromethylalkynes
Online Access:	http://www.mdpi.com/1420-3049/19/2/1763

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