Does Epiphora Cause Meibomian Gland Loss and Dry Eye?
Purpose To investigate the effects of epiphora due to primary acquired nasolacrimal duct obstruction (PANDO) and external dacryocystorhinostomy (DCR) for its treatment on meibomian glands and tear film parameters. Methods External DCR for unilateral PANDO in the Department of Ophthalmology, Faculty...
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| Format: | Article |
| Language: | English |
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Clinical and Experimental Ocular Trauma and Infection
2024-01-01
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| Series: | Clinical and Experimental Ocular Trauma and Infection |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/3619776 |
| _version_ | 1797356304610623488 |
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| author | Berna Akova Sertaç Argun Kıvanç Kübra Tinç |
| author_facet | Berna Akova Sertaç Argun Kıvanç Kübra Tinç |
| author_sort | Berna Akova |
| collection | DOAJ |
| description | Purpose
To investigate the effects of epiphora due to primary acquired nasolacrimal duct
obstruction (PANDO) and external dacryocystorhinostomy (DCR) for its treatment on meibomian glands and tear film parameters.
Methods
External DCR for unilateral PANDO in the Department of Ophthalmology, Faculty of Medicine, Bursa Uludag University between January 2018-June 2019 were reviewed. The tear film parameters and meibography measurement recorded at the preoperative and follow-up examinations were examined on both the obstructed side and the patent side. SPSS 23 was used for statistical analyzed.
Results
There was a significant difference between Schirmer-1 score before external DCR (13,1±5,0; 6,3±5,0; p=0,01) and this difference disappeared after surgery (12,0±7,3; 7,7±5,0; p=0,06). Postoperative increase in non-invasive average break-up time (niAVG-BUT) on operated side was statistically significant (10,5±4,6; 12,0±5,3; p=0,033). When the healthy and operated sides were compared with each other, no significant difference was observed in niAVG-BUT before and after surgery (p=0,907, p=0,614). Mean meibomian gland losses were decreased in both operated and patent sides postoperatively and these values were statistically significant (33,0±8,2; 27,1±6,8; p<0,001, 37,3±10,4; 31,4±9,6; p=0,01).
Conclusion
Patients with unilateral nasolacrimal duct obstruction (NLDO) had loss of meibomian gland in both NLDO side and patent side. This loss was found to be significantly reduced on both obstructed and patent sides after successful surgical removal of the epiphora. |
| first_indexed | 2024-03-08T14:24:41Z |
| format | Article |
| id | doaj.art-ea67d45546574ce3a93f76152808bc33 |
| institution | Directory Open Access Journal |
| issn | 2667-8462 |
| language | English |
| last_indexed | 2024-03-08T14:24:41Z |
| publishDate | 2024-01-01 |
| publisher | Clinical and Experimental Ocular Trauma and Infection |
| record_format | Article |
| series | Clinical and Experimental Ocular Trauma and Infection |
| spelling | doaj.art-ea67d45546574ce3a93f76152808bc332024-01-13T09:32:34ZengClinical and Experimental Ocular Trauma and InfectionClinical and Experimental Ocular Trauma and Infection2667-84622024-01-015116251411Does Epiphora Cause Meibomian Gland Loss and Dry Eye?Berna Akova0Sertaç Argun Kıvanç1Kübra Tinç2BURSA ULUDAG UNIVERSITYBURSA ULUDAG UNIVERSITYUNIVERSITY OF HEALTH SCIENCES, ERZURUM REGION HEALTH RESEARCH CENTERPurpose To investigate the effects of epiphora due to primary acquired nasolacrimal duct obstruction (PANDO) and external dacryocystorhinostomy (DCR) for its treatment on meibomian glands and tear film parameters. Methods External DCR for unilateral PANDO in the Department of Ophthalmology, Faculty of Medicine, Bursa Uludag University between January 2018-June 2019 were reviewed. The tear film parameters and meibography measurement recorded at the preoperative and follow-up examinations were examined on both the obstructed side and the patent side. SPSS 23 was used for statistical analyzed. Results There was a significant difference between Schirmer-1 score before external DCR (13,1±5,0; 6,3±5,0; p=0,01) and this difference disappeared after surgery (12,0±7,3; 7,7±5,0; p=0,06). Postoperative increase in non-invasive average break-up time (niAVG-BUT) on operated side was statistically significant (10,5±4,6; 12,0±5,3; p=0,033). When the healthy and operated sides were compared with each other, no significant difference was observed in niAVG-BUT before and after surgery (p=0,907, p=0,614). Mean meibomian gland losses were decreased in both operated and patent sides postoperatively and these values were statistically significant (33,0±8,2; 27,1±6,8; p<0,001, 37,3±10,4; 31,4±9,6; p=0,01). Conclusion Patients with unilateral nasolacrimal duct obstruction (NLDO) had loss of meibomian gland in both NLDO side and patent side. This loss was found to be significantly reduced on both obstructed and patent sides after successful surgical removal of the epiphora.https://dergipark.org.tr/tr/download/article-file/3619776epiphorameibomian glanddacryocystorhinostomydry eyemeibographyophthalmology |
| spellingShingle | Berna Akova Sertaç Argun Kıvanç Kübra Tinç Does Epiphora Cause Meibomian Gland Loss and Dry Eye? Clinical and Experimental Ocular Trauma and Infection epiphora meibomian gland dacryocystorhinostomy dry eye meibography ophthalmology |
| title | Does Epiphora Cause Meibomian Gland Loss and Dry Eye? |
| title_full | Does Epiphora Cause Meibomian Gland Loss and Dry Eye? |
| title_fullStr | Does Epiphora Cause Meibomian Gland Loss and Dry Eye? |
| title_full_unstemmed | Does Epiphora Cause Meibomian Gland Loss and Dry Eye? |
| title_short | Does Epiphora Cause Meibomian Gland Loss and Dry Eye? |
| title_sort | does epiphora cause meibomian gland loss and dry eye |
| topic | epiphora meibomian gland dacryocystorhinostomy dry eye meibography ophthalmology |
| url | https://dergipark.org.tr/tr/download/article-file/3619776 |
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