2′-Hydroxycinnamaldehyde mitigates acetaminophen-induced acute liver injury by inhibiting the Warburg effect-mediated pyroptosis via the PKM2-NLRP3 axis
Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver injury. However, the underlying mechanisms appear to be multifaceted and there are few effective treatments. In this study, we used the 2′-Hydroxycinnamaldehyde (HCA), an active ingredient extracted from cinnamon stem bar...
Үндсэн зохиолчид: | , , , , , , , , , , , , , , |
---|---|
Формат: | Өгүүллэг |
Хэл сонгох: | English |
Хэвлэсэн: |
Elsevier
2023-11-01
|
Цуврал: | Journal of Functional Foods |
Нөхцлүүд: | |
Онлайн хандалт: | http://www.sciencedirect.com/science/article/pii/S1756464623004723 |