Alteration of the Basal Membrane Integrity in Orthodontic Treatment–Induced Gingival Enlargement
Introduction: Orthodontic treatment–induced gingival enlargement is a progressive, localized or generalized increase in gingival tissue. Objective: To determine morphologic aspects in the basal membrane of the gingival tissue in patients with orthodontic treatment–induced gingival enlargement. Met...
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| Format: | Article |
| Language: | English |
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Editorial Ciencias Médicas
2023-10-01
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| Series: | Revista Cubana de Estomatología |
| Subjects: | |
| Online Access: | https://revestomatologia.sld.cu/index.php/est/article/view/4543 |
| _version_ | 1827356890528481280 |
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| author | Victor Hugo Simancas Escorcia Alejandra Herrera-Herrera Antonio Díaz Caballero |
| author_facet | Victor Hugo Simancas Escorcia Alejandra Herrera-Herrera Antonio Díaz Caballero |
| author_sort | Victor Hugo Simancas Escorcia |
| collection | DOAJ |
| description | Introduction: Orthodontic treatment–induced gingival enlargement is a progressive, localized or generalized increase in gingival tissue.
Objective: To determine morphologic aspects in the basal membrane of the gingival tissue in patients with orthodontic treatment–induced gingival enlargement.
Methods: A descriptive and cross-sectional study was carried out, in which gingival tissues of patients with orthodontic treatment–induced gingival enlargement (test group: n=5) and healthy individuals (control group: n=5) were analyzed by histological and immunohistochemical analysis with the polyclonal antibody anticytokeratin 14. Grade 1 and grade 2 disrupted basal membrane were identified. The statistical program R (version 4.0.2) for Windows was used. Significance was declared if p was greater than 0.05.
Results: The presence of disrupted basal membranes was observed in all the patients from the test group. These individuals presented a greater number of morphological changes in the gingival tissue. Compared to the control group (p < 0.001), statistically significant values were observed for cases of disrupted basal membrane (grade I) and disruptions surrounded by epithelial cells or gingival fibroblasts (grade II).
Conclusion: The epithelial tissue of patients with orthodontic treatment–induced gingival enlargement shows an evident loss of the basal membrane integrity. These discontinuities are suggestive of a considerable increase in epithelial plasticity in patients with orthodontic treatment–induced gingival enlargement. |
| first_indexed | 2024-03-08T05:16:33Z |
| format | Article |
| id | doaj.art-ea69f72de62c4b0aa8fabc4b1171a9ba |
| institution | Directory Open Access Journal |
| issn | 0034-7507 1561-297X |
| language | English |
| last_indexed | 2024-03-08T05:16:33Z |
| publishDate | 2023-10-01 |
| publisher | Editorial Ciencias Médicas |
| record_format | Article |
| series | Revista Cubana de Estomatología |
| spelling | doaj.art-ea69f72de62c4b0aa8fabc4b1171a9ba2024-02-06T21:36:42ZengEditorial Ciencias MédicasRevista Cubana de Estomatología0034-75071561-297X2023-10-01603e4543e45431236Alteration of the Basal Membrane Integrity in Orthodontic Treatment–Induced Gingival EnlargementVictor Hugo Simancas Escorcia0Alejandra Herrera-Herrera1Antonio Díaz Caballero2Universidad del Sinú - Cartagena. Facultad de Ciencias de la Salud. Grupo GENOMA. Cartagena, Colombia.Universidad Metropolitana – Barranquilla, Colombia.Universidad de Cartagena. Facultad de Odontología. Grupo interdisciplinario de investigaciones y tratamientos odontológicos Universidad de Cartagena (GITOUC). Cartagena, Colombia.Introduction: Orthodontic treatment–induced gingival enlargement is a progressive, localized or generalized increase in gingival tissue. Objective: To determine morphologic aspects in the basal membrane of the gingival tissue in patients with orthodontic treatment–induced gingival enlargement. Methods: A descriptive and cross-sectional study was carried out, in which gingival tissues of patients with orthodontic treatment–induced gingival enlargement (test group: n=5) and healthy individuals (control group: n=5) were analyzed by histological and immunohistochemical analysis with the polyclonal antibody anticytokeratin 14. Grade 1 and grade 2 disrupted basal membrane were identified. The statistical program R (version 4.0.2) for Windows was used. Significance was declared if p was greater than 0.05. Results: The presence of disrupted basal membranes was observed in all the patients from the test group. These individuals presented a greater number of morphological changes in the gingival tissue. Compared to the control group (p < 0.001), statistically significant values were observed for cases of disrupted basal membrane (grade I) and disruptions surrounded by epithelial cells or gingival fibroblasts (grade II). Conclusion: The epithelial tissue of patients with orthodontic treatment–induced gingival enlargement shows an evident loss of the basal membrane integrity. These discontinuities are suggestive of a considerable increase in epithelial plasticity in patients with orthodontic treatment–induced gingival enlargement.https://revestomatologia.sld.cu/index.php/est/article/view/4543sobrecrecimiento gingivalmembrana basalortodonciaencíatransición epitelial-mesénquima. |
| spellingShingle | Victor Hugo Simancas Escorcia Alejandra Herrera-Herrera Antonio Díaz Caballero Alteration of the Basal Membrane Integrity in Orthodontic Treatment–Induced Gingival Enlargement Revista Cubana de Estomatología sobrecrecimiento gingival membrana basal ortodoncia encía transición epitelial-mesénquima. |
| title | Alteration of the Basal Membrane Integrity in Orthodontic Treatment–Induced Gingival Enlargement |
| title_full | Alteration of the Basal Membrane Integrity in Orthodontic Treatment–Induced Gingival Enlargement |
| title_fullStr | Alteration of the Basal Membrane Integrity in Orthodontic Treatment–Induced Gingival Enlargement |
| title_full_unstemmed | Alteration of the Basal Membrane Integrity in Orthodontic Treatment–Induced Gingival Enlargement |
| title_short | Alteration of the Basal Membrane Integrity in Orthodontic Treatment–Induced Gingival Enlargement |
| title_sort | alteration of the basal membrane integrity in orthodontic treatment induced gingival enlargement |
| topic | sobrecrecimiento gingival membrana basal ortodoncia encía transición epitelial-mesénquima. |
| url | https://revestomatologia.sld.cu/index.php/est/article/view/4543 |
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