Detection of Extended-Spectrum ß-Lactamases in Gram Negative Bacilli Isolated from Intensive–Care Units
Resistance to broad spectrum ß-lactam antibiotics due to extended-spectrum ß-lactamases (ESBL) has emerged in clinical gram negative isolates, but with considerable variation between hospitals. In this study; ESBL in clinical gram negative isolates were detected by investigating the synergistic effe...
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| Format: | Article |
| Language: | English |
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Bilimsel Tip Yayinevi
1997-06-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=1997-2-2-105-108.pdf |
| _version_ | 1797908920602198016 |
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| author | Neşe EVRENSEL A. Nedret KOÇ Bülent SÜMERKAN |
| author_facet | Neşe EVRENSEL A. Nedret KOÇ Bülent SÜMERKAN |
| author_sort | Neşe EVRENSEL |
| collection | DOAJ |
| description | Resistance to broad spectrum ß-lactam antibiotics due to extended-spectrum ß-lactamases (ESBL) has emerged in clinical gram negative isolates, but with considerable variation between hospitals. In this study; ESBL in clinical gram negative isolates were detected by investigating the synergistic effect of the combination of clavulanic acid+amoxicillin (AMC) with cefotaxime (CTX), ceftazidime (CAZ) and aztreonam (ATM) in double disk synergy test. 105 clinical isolates from the patients in intensive-care units were comprising 50 Kebsiella spp, 14 Enterobacter spp, 19 E. coli, 11 P. aeruginosa, 9 nonfermentative gram negative bacilli (NGNB) and 2 Citrobacter spp. Synergistic effect with CTX, CAZ and ATM was detected in 34% of Klebsiella spp (17/50), 57.8% of E. Coli (11/19), 18.2% of P. aeruginosa (2/11), 14.2% of Enterobacter spp (2/14) and 11.1% of NGNB (1/9). |
| first_indexed | 2024-04-10T11:01:33Z |
| format | Article |
| id | doaj.art-ea6fa6f362184cd4baecb688ce3b0db9 |
| institution | Directory Open Access Journal |
| issn | 1300-932X 1300-932X |
| language | English |
| last_indexed | 2024-04-10T11:01:33Z |
| publishDate | 1997-06-01 |
| publisher | Bilimsel Tip Yayinevi |
| record_format | Article |
| series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| spelling | doaj.art-ea6fa6f362184cd4baecb688ce3b0db92023-02-15T16:19:42ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X1997-06-0122105108Detection of Extended-Spectrum ß-Lactamases in Gram Negative Bacilli Isolated from Intensive–Care UnitsNeşe EVRENSEL0A. Nedret KOÇ1Bülent SÜMERKAN2Erciyes Üniversitesi Tıp Fakültesi Mikrobiyoloji Anabilim Dalı, KAYSERİErciyes Üniversitesi Tıp Fakültesi Mikrobiyoloji Anabilim Dalı, KAYSERİErciyes Üniversitesi Tıp Fakültesi Mikrobiyoloji Anabilim Dalı, KAYSERİResistance to broad spectrum ß-lactam antibiotics due to extended-spectrum ß-lactamases (ESBL) has emerged in clinical gram negative isolates, but with considerable variation between hospitals. In this study; ESBL in clinical gram negative isolates were detected by investigating the synergistic effect of the combination of clavulanic acid+amoxicillin (AMC) with cefotaxime (CTX), ceftazidime (CAZ) and aztreonam (ATM) in double disk synergy test. 105 clinical isolates from the patients in intensive-care units were comprising 50 Kebsiella spp, 14 Enterobacter spp, 19 E. coli, 11 P. aeruginosa, 9 nonfermentative gram negative bacilli (NGNB) and 2 Citrobacter spp. Synergistic effect with CTX, CAZ and ATM was detected in 34% of Klebsiella spp (17/50), 57.8% of E. Coli (11/19), 18.2% of P. aeruginosa (2/11), 14.2% of Enterobacter spp (2/14) and 11.1% of NGNB (1/9).http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=1997-2-2-105-108.pdfExtended Spectrum ß-LactamasesDouble Disk Synergy Test |
| spellingShingle | Neşe EVRENSEL A. Nedret KOÇ Bülent SÜMERKAN Detection of Extended-Spectrum ß-Lactamases in Gram Negative Bacilli Isolated from Intensive–Care Units Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Extended Spectrum ß-Lactamases Double Disk Synergy Test |
| title | Detection of Extended-Spectrum ß-Lactamases in Gram Negative Bacilli Isolated from Intensive–Care Units |
| title_full | Detection of Extended-Spectrum ß-Lactamases in Gram Negative Bacilli Isolated from Intensive–Care Units |
| title_fullStr | Detection of Extended-Spectrum ß-Lactamases in Gram Negative Bacilli Isolated from Intensive–Care Units |
| title_full_unstemmed | Detection of Extended-Spectrum ß-Lactamases in Gram Negative Bacilli Isolated from Intensive–Care Units |
| title_short | Detection of Extended-Spectrum ß-Lactamases in Gram Negative Bacilli Isolated from Intensive–Care Units |
| title_sort | detection of extended spectrum ss lactamases in gram negative bacilli isolated from intensive care units |
| topic | Extended Spectrum ß-Lactamases Double Disk Synergy Test |
| url | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=1997-2-2-105-108.pdf |
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