Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes
The present study aimed to evaluate the histological changes and adverse effects on the total protein and general carbohydrates in the lung and small intestine of guinea pig "Cavia porcellus" induced by the exposure to sub lethal doses of the organophosphate insecticide diazinon. Primarily...
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| Format: | Article |
| Language: | English |
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Instituto de Tecnologia do Paraná (Tecpar)
2009-04-01
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| Series: | Brazilian Archives of Biology and Technology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200008 |
| _version_ | 1818361327164325888 |
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| author | Mohamed Ibrahim Rady |
| author_facet | Mohamed Ibrahim Rady |
| author_sort | Mohamed Ibrahim Rady |
| collection | DOAJ |
| description | The present study aimed to evaluate the histological changes and adverse effects on the total protein and general carbohydrates in the lung and small intestine of guinea pig "Cavia porcellus" induced by the exposure to sub lethal doses of the organophosphate insecticide diazinon. Primarily, diazinon insecticide oral LD50 was investigated after administrating orally different doses in guinea pig and was determined as 213 mg/Kg bw., the animals exposed to sub lethal doses of this insecticide revealed histological changes in both lung and intestine in a dose dependent manner. Also, significant decrease in the total protein and general carbohydrates in the lung and intestine were mostly observed, especially with the higher doses of the insecticide in comparison with control group. |
| first_indexed | 2024-12-13T21:14:55Z |
| format | Article |
| id | doaj.art-ea756d5bf75540f6b2de69b02fe9844e |
| institution | Directory Open Access Journal |
| issn | 1516-8913 1678-4324 |
| language | English |
| last_indexed | 2024-12-13T21:14:55Z |
| publishDate | 2009-04-01 |
| publisher | Instituto de Tecnologia do Paraná (Tecpar) |
| record_format | Article |
| series | Brazilian Archives of Biology and Technology |
| spelling | doaj.art-ea756d5bf75540f6b2de69b02fe9844e2022-12-21T23:31:16ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1516-89131678-43242009-04-0152231732610.1590/S1516-89132009000200008Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changesMohamed Ibrahim RadyThe present study aimed to evaluate the histological changes and adverse effects on the total protein and general carbohydrates in the lung and small intestine of guinea pig "Cavia porcellus" induced by the exposure to sub lethal doses of the organophosphate insecticide diazinon. Primarily, diazinon insecticide oral LD50 was investigated after administrating orally different doses in guinea pig and was determined as 213 mg/Kg bw., the animals exposed to sub lethal doses of this insecticide revealed histological changes in both lung and intestine in a dose dependent manner. Also, significant decrease in the total protein and general carbohydrates in the lung and intestine were mostly observed, especially with the higher doses of the insecticide in comparison with control group.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200008DiazinonGuinea pigLungIntestine |
| spellingShingle | Mohamed Ibrahim Rady Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes Brazilian Archives of Biology and Technology Diazinon Guinea pig Lung Intestine |
| title | Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes |
| title_full | Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes |
| title_fullStr | Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes |
| title_full_unstemmed | Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes |
| title_short | Effects of exposure to Diazinon on the lung and small intestine of Guinea pig, histological and some histochemical changes |
| title_sort | effects of exposure to diazinon on the lung and small intestine of guinea pig histological and some histochemical changes |
| topic | Diazinon Guinea pig Lung Intestine |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000200008 |
| work_keys_str_mv | AT mohamedibrahimrady effectsofexposuretodiazinononthelungandsmallintestineofguineapighistologicalandsomehistochemicalchanges |