Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements
Aedes aegypti transmit pathogenic arboviruses while the mosquito itself tolerates the infection. We examine a piRNA-based immunity that relies on the acquisition of viral derived cDNA (vDNA) and how this pathway discriminates between self and non-self. The piRNAs derived from these vDNAs are essenti...
Main Authors: | Michel Tassetto, Mark Kunitomi, Zachary J Whitfield, Patrick T Dolan, Irma Sánchez-Vargas, Miguel Garcia-Knight, Isabel Ribiero, Taotao Chen, Ken E Olson, Raul Andino |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/41244 |
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