Burkholderia pseudomallei peri-prosthetic infection following medial malleolar internal fixation: a case report

Abstract Background Melioidosis-associated peri-prosthetic infection is extremely rare. To date, melioidosis associated septic arthritis of the ankle joint following a medial malleolar internal fixation has not been reported. Case presentation We describe a 49-year-old male with a history of long st...

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Main Authors: Umesh Jayarajah, Arulprashanth Arulanantham, Vimaleswaran Koculen, Chamikara Palkumbura, Aadil Faleel, Rukshan Sooriyarachchi
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Infectious Diseases
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12879-020-04967-y
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author Umesh Jayarajah
Arulprashanth Arulanantham
Vimaleswaran Koculen
Chamikara Palkumbura
Aadil Faleel
Rukshan Sooriyarachchi
author_facet Umesh Jayarajah
Arulprashanth Arulanantham
Vimaleswaran Koculen
Chamikara Palkumbura
Aadil Faleel
Rukshan Sooriyarachchi
author_sort Umesh Jayarajah
collection DOAJ
description Abstract Background Melioidosis-associated peri-prosthetic infection is extremely rare. To date, melioidosis associated septic arthritis of the ankle joint following a medial malleolar internal fixation has not been reported. Case presentation We describe a 49-year-old male with a history of long standing diabetes who presented with fever, constitutional symptoms and right ankle pain for 1 week. Ten years ago, he underwent a medial malleolar screw fixation following a traumatic closed fracture. His initial right ankle radiographs showed no evidence of osteomyelitis. He underwent a wound debridement and washout of the right ankle joint. The peripheral blood and pus from the ankle joint was culture positive for Burkholderia pseudomallei with very high antibody titres. His subsequent radiographs showed features of chronic osteomyelitis. He was treated with a prolonged course of antibiotics and repeated wound debridement. At follow up after 6 months, he had no clinical features of recurrent infection. Conclusions Melioidosis should be entertained in the differential diagnosis of peri-prosthetic infections in high risk patients.
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spelling doaj.art-ea7aa2343d904413be01cdb4ea5a9a4a2022-12-22T03:38:50ZengBMCBMC Infectious Diseases1471-23342020-03-012011510.1186/s12879-020-04967-yBurkholderia pseudomallei peri-prosthetic infection following medial malleolar internal fixation: a case reportUmesh Jayarajah0Arulprashanth Arulanantham1Vimaleswaran Koculen2Chamikara Palkumbura3Aadil Faleel4Rukshan Sooriyarachchi5Department of Orthopaedics and Trauma, National Hospital of Sri LankaDepartment of Orthopaedics and Trauma, National Hospital of Sri LankaDepartment of Orthopaedics and Trauma, National Hospital of Sri LankaDepartment of Orthopaedics and Trauma, National Hospital of Sri LankaDepartment of Orthopaedics and Trauma, National Hospital of Sri LankaDepartment of Orthopaedics and Trauma, National Hospital of Sri LankaAbstract Background Melioidosis-associated peri-prosthetic infection is extremely rare. To date, melioidosis associated septic arthritis of the ankle joint following a medial malleolar internal fixation has not been reported. Case presentation We describe a 49-year-old male with a history of long standing diabetes who presented with fever, constitutional symptoms and right ankle pain for 1 week. Ten years ago, he underwent a medial malleolar screw fixation following a traumatic closed fracture. His initial right ankle radiographs showed no evidence of osteomyelitis. He underwent a wound debridement and washout of the right ankle joint. The peripheral blood and pus from the ankle joint was culture positive for Burkholderia pseudomallei with very high antibody titres. His subsequent radiographs showed features of chronic osteomyelitis. He was treated with a prolonged course of antibiotics and repeated wound debridement. At follow up after 6 months, he had no clinical features of recurrent infection. Conclusions Melioidosis should be entertained in the differential diagnosis of peri-prosthetic infections in high risk patients.http://link.springer.com/article/10.1186/s12879-020-04967-yMelioidosisBurkholderia pseudomalleiPeri-prosthetic infectionMedial malleolar internal fixationScrew fixationChronic osteomyelitis
spellingShingle Umesh Jayarajah
Arulprashanth Arulanantham
Vimaleswaran Koculen
Chamikara Palkumbura
Aadil Faleel
Rukshan Sooriyarachchi
Burkholderia pseudomallei peri-prosthetic infection following medial malleolar internal fixation: a case report
BMC Infectious Diseases
Melioidosis
Burkholderia pseudomallei
Peri-prosthetic infection
Medial malleolar internal fixation
Screw fixation
Chronic osteomyelitis
title Burkholderia pseudomallei peri-prosthetic infection following medial malleolar internal fixation: a case report
title_full Burkholderia pseudomallei peri-prosthetic infection following medial malleolar internal fixation: a case report
title_fullStr Burkholderia pseudomallei peri-prosthetic infection following medial malleolar internal fixation: a case report
title_full_unstemmed Burkholderia pseudomallei peri-prosthetic infection following medial malleolar internal fixation: a case report
title_short Burkholderia pseudomallei peri-prosthetic infection following medial malleolar internal fixation: a case report
title_sort burkholderia pseudomallei peri prosthetic infection following medial malleolar internal fixation a case report
topic Melioidosis
Burkholderia pseudomallei
Peri-prosthetic infection
Medial malleolar internal fixation
Screw fixation
Chronic osteomyelitis
url http://link.springer.com/article/10.1186/s12879-020-04967-y
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