Adult-Onset Still’s Disease following Coronavirus 2 (SARS-CoV-2) Vaccination: A Case Report
In recent years, during the ravages of COVID-19, a variety of vaccines have been developed and are now on the market. However, although these new vaccines have undergone various trials, there are still many unknown side effects. We report a case of a 30-year-old woman who presented with general weak...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/10/10/1687 |
| _version_ | 1797469737012166656 |
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| author | Xiang-He Chua Wea-Lung Lin Yuan-Ti Lee |
| author_facet | Xiang-He Chua Wea-Lung Lin Yuan-Ti Lee |
| author_sort | Xiang-He Chua |
| collection | DOAJ |
| description | In recent years, during the ravages of COVID-19, a variety of vaccines have been developed and are now on the market. However, although these new vaccines have undergone various trials, there are still many unknown side effects. We report a case of a 30-year-old woman who presented with general weakness, sore throat, generalized skin rashes, symmetrical arthralgia, and persistent fever of up to 40 °C with onset 16 days after receiving the Moderna COVID-19 vaccine. Adult-onset Still’s disease (AOSD) was diagnosed according to Yamaguchi’s criteria after excluding the feasibility of infectious diseases, autoimmune diseases, and malignancies. In particular, her responses to glucocorticoids and naproxen were significant and inversely proportional to her use of empirical antibiotics in the initial stage of treatment. We studied some similar cases of AOSD, which also considered the adverse effects of COVID-19 vaccination and suggested the immunogenicity and possibility of inflammatory responses related to COVID-19 vaccination. |
| first_indexed | 2024-03-09T19:24:26Z |
| format | Article |
| id | doaj.art-ea7b00d8f6f44c92bc7c978427ab275d |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T19:24:26Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-ea7b00d8f6f44c92bc7c978427ab275d2023-11-24T03:04:17ZengMDPI AGVaccines2076-393X2022-10-011010168710.3390/vaccines10101687Adult-Onset Still’s Disease following Coronavirus 2 (SARS-CoV-2) Vaccination: A Case ReportXiang-He Chua0Wea-Lung Lin1Yuan-Ti Lee2School of Medicine, Chung Shan Medical University, Taichung City 40201, TaiwanSchool of Medicine, Chung Shan Medical University, Taichung City 40201, TaiwanSchool of Medicine, Chung Shan Medical University, Taichung City 40201, TaiwanIn recent years, during the ravages of COVID-19, a variety of vaccines have been developed and are now on the market. However, although these new vaccines have undergone various trials, there are still many unknown side effects. We report a case of a 30-year-old woman who presented with general weakness, sore throat, generalized skin rashes, symmetrical arthralgia, and persistent fever of up to 40 °C with onset 16 days after receiving the Moderna COVID-19 vaccine. Adult-onset Still’s disease (AOSD) was diagnosed according to Yamaguchi’s criteria after excluding the feasibility of infectious diseases, autoimmune diseases, and malignancies. In particular, her responses to glucocorticoids and naproxen were significant and inversely proportional to her use of empirical antibiotics in the initial stage of treatment. We studied some similar cases of AOSD, which also considered the adverse effects of COVID-19 vaccination and suggested the immunogenicity and possibility of inflammatory responses related to COVID-19 vaccination.https://www.mdpi.com/2076-393X/10/10/1687adult-onset Still’s diseaseCOVID-19 vaccinesmRNA COVID-19 vaccine |
| spellingShingle | Xiang-He Chua Wea-Lung Lin Yuan-Ti Lee Adult-Onset Still’s Disease following Coronavirus 2 (SARS-CoV-2) Vaccination: A Case Report Vaccines adult-onset Still’s disease COVID-19 vaccines mRNA COVID-19 vaccine |
| title | Adult-Onset Still’s Disease following Coronavirus 2 (SARS-CoV-2) Vaccination: A Case Report |
| title_full | Adult-Onset Still’s Disease following Coronavirus 2 (SARS-CoV-2) Vaccination: A Case Report |
| title_fullStr | Adult-Onset Still’s Disease following Coronavirus 2 (SARS-CoV-2) Vaccination: A Case Report |
| title_full_unstemmed | Adult-Onset Still’s Disease following Coronavirus 2 (SARS-CoV-2) Vaccination: A Case Report |
| title_short | Adult-Onset Still’s Disease following Coronavirus 2 (SARS-CoV-2) Vaccination: A Case Report |
| title_sort | adult onset still s disease following coronavirus 2 sars cov 2 vaccination a case report |
| topic | adult-onset Still’s disease COVID-19 vaccines mRNA COVID-19 vaccine |
| url | https://www.mdpi.com/2076-393X/10/10/1687 |
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