Integrated genomic, proteomic and cognitive assessment in Duchenne Muscular Dystrophy suggest astrocyte centric pathology

Integrated genomic, proteomic and cognitive assessment in Duchenne Muscular Dystrophy suggest astrocyte centric pathology

Introduction: Documented Duchenne Muscular Dystrophy (DMD) biomarkers are confined to Caucasians and are poor indicators of cognitive difficulties and neuropsychological alterations. Materials and methods: This study correlates serum protein signatures with cognitive performance in DMD patients of S...

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Bibliographic Details
Main Authors: Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Pulasthi Dissanayaka, Isuru Gunarathne, Dhammika Amaratunga, Roshan Liyanage, Sunethra Senanayaka, Saraji Wijesekara, Hemal H. Gunasekara, Kamala Vanarsa, Jessica Castillo, Yetrib Hathout, Ashwin Dalal, Harry W.M. Steinbusch, Eric Hoffman, Chandra Mohan, K. Ranil D. de Silva
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
Brain regions
Intelligence
Memory
Dp71
Dp140
Alzheimer’s disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023057389

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