Clinical Features of Mycetoma and the Appropriate Treatment Options

Pooja Agarwal, Ashish Jagati, Santoshdev P Rathod, Kirti Kalra, Shefali Patel, Malay Chaudhari Department of Dermatology, Smt. SCL Hospital, Smt. N.H.L. Municipal Medical College, Ahmedabad, Gujarat, IndiaCorrespondence: Kirti KalraDepartment of Dermatology, Smt. SCL Hospital, Smt. N.H.L. Municipal...

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Main Authors: Agarwal P, Jagati A, Rathod SP, Kalra K, Patel S, Chaudhari M
Format: Article
Language:English
Published: Dove Medical Press 2021-07-01
Series:Research and Reports in Tropical Medicine
Subjects:
Online Access:https://www.dovepress.com/clinical-features-of-mycetoma-and-the-appropriate-treatment-options-peer-reviewed-fulltext-article-RRTM
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author Agarwal P
Jagati A
Rathod SP
Kalra K
Patel S
Chaudhari M
author_facet Agarwal P
Jagati A
Rathod SP
Kalra K
Patel S
Chaudhari M
author_sort Agarwal P
collection DOAJ
description Pooja Agarwal, Ashish Jagati, Santoshdev P Rathod, Kirti Kalra, Shefali Patel, Malay Chaudhari Department of Dermatology, Smt. SCL Hospital, Smt. N.H.L. Municipal Medical College, Ahmedabad, Gujarat, IndiaCorrespondence: Kirti KalraDepartment of Dermatology, Smt. SCL Hospital, Smt. N.H.L. Municipal Medical College, OPD Room No. 16, Ahmedabad, Gujarat, IndiaTel +91 9416917766Email kirtidudeja69@gmail.comAbstract: Mycetoma is a chronic, suppurative and debilitating granulomatous infection seen mainly in tropical and subtropical areas and is now declared as a neglected tropical disease by the World Health Organization. The clinical diagnosis is usually characterized by a classical triad of localized swelling, underlying sinus tracts, and production of grains or granules, but unusual presentations are also seen. It is classified into eumycetoma caused by the fungus, and actinomycetoma caused by the bacteria. The clinical presentation of both is almost similar and a definite diagnosis is essential before starting the treatment as it differs for both. Surgical debulking followed by a prolonged course of medical therapy now forms the mainstay of treatment due to the long course of the disease and suboptimal response. This review focuses on the various usual as well as unusual clinical presentations of mycetoma, established treatment regimens as well as recent changes in the mode of administration of drugs and newer drugs for mycetoma.Keywords: actinomycetoma, eumycetoma, Madura foot, treatment
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spelling doaj.art-ea84f44e9fa747818c86b3c33d26fa652022-12-21T18:42:39ZengDove Medical PressResearch and Reports in Tropical Medicine1179-72822021-07-01Volume 1217317966733Clinical Features of Mycetoma and the Appropriate Treatment OptionsAgarwal PJagati ARathod SPKalra KPatel SChaudhari MPooja Agarwal, Ashish Jagati, Santoshdev P Rathod, Kirti Kalra, Shefali Patel, Malay Chaudhari Department of Dermatology, Smt. SCL Hospital, Smt. N.H.L. Municipal Medical College, Ahmedabad, Gujarat, IndiaCorrespondence: Kirti KalraDepartment of Dermatology, Smt. SCL Hospital, Smt. N.H.L. Municipal Medical College, OPD Room No. 16, Ahmedabad, Gujarat, IndiaTel +91 9416917766Email kirtidudeja69@gmail.comAbstract: Mycetoma is a chronic, suppurative and debilitating granulomatous infection seen mainly in tropical and subtropical areas and is now declared as a neglected tropical disease by the World Health Organization. The clinical diagnosis is usually characterized by a classical triad of localized swelling, underlying sinus tracts, and production of grains or granules, but unusual presentations are also seen. It is classified into eumycetoma caused by the fungus, and actinomycetoma caused by the bacteria. The clinical presentation of both is almost similar and a definite diagnosis is essential before starting the treatment as it differs for both. Surgical debulking followed by a prolonged course of medical therapy now forms the mainstay of treatment due to the long course of the disease and suboptimal response. This review focuses on the various usual as well as unusual clinical presentations of mycetoma, established treatment regimens as well as recent changes in the mode of administration of drugs and newer drugs for mycetoma.Keywords: actinomycetoma, eumycetoma, Madura foot, treatmenthttps://www.dovepress.com/clinical-features-of-mycetoma-and-the-appropriate-treatment-options-peer-reviewed-fulltext-article-RRTMactinomycetomaeumycetomamadura foottreatment
spellingShingle Agarwal P
Jagati A
Rathod SP
Kalra K
Patel S
Chaudhari M
Clinical Features of Mycetoma and the Appropriate Treatment Options
Research and Reports in Tropical Medicine
actinomycetoma
eumycetoma
madura foot
treatment
title Clinical Features of Mycetoma and the Appropriate Treatment Options
title_full Clinical Features of Mycetoma and the Appropriate Treatment Options
title_fullStr Clinical Features of Mycetoma and the Appropriate Treatment Options
title_full_unstemmed Clinical Features of Mycetoma and the Appropriate Treatment Options
title_short Clinical Features of Mycetoma and the Appropriate Treatment Options
title_sort clinical features of mycetoma and the appropriate treatment options
topic actinomycetoma
eumycetoma
madura foot
treatment
url https://www.dovepress.com/clinical-features-of-mycetoma-and-the-appropriate-treatment-options-peer-reviewed-fulltext-article-RRTM
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