Integrated Quality by Design Approach for Developing Nanolipidic Drug Delivery Systems of Olmesartan Medoxomil with Enhanced Antihypertensive Action

Integrated Quality by Design Approach for Developing Nanolipidic Drug Delivery Systems of Olmesartan Medoxomil with Enhanced Antihypertensive Action

Purpose: The present work endeavors to report a systematic approach of developing the lipidic self-nanoemulsifying formulation of olmesartan medoxomil (OMT) on the principles of Quality by Design (QbD). Methods: For preparing the self-nanoemulsifying formulation, a mixture of oil, surfactant and cos...

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Bibliographic Details
Main Authors: Jagdish Kumar Arun, Rajeshwar Vodeti, Birendra Shrivastava, Vasudha Bakshi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-05-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
bioavailability
nanoemulsion
optimization
experimental design
pharmacokinetics
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-27965

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