Molecular Mechanisms and Therapeutic Implications of Human Pericyte-like Adipose-Derived Mesenchymal Stem Cells in an In Vitro Model of Diabetic Retinopathy

Molecular Mechanisms and Therapeutic Implications of Human Pericyte-like Adipose-Derived Mesenchymal Stem Cells in an In Vitro Model of Diabetic Retinopathy

The blood–retinal barrier (BRB) is strongly compromised in diabetic retinopathy (DR) due to the detachment of pericytes (PCs) from retinal microvessels, resulting in increased permeability and impairment of the BRB. Western blots, immunofluorescence and ELISA were performed on adipose mesenchymal st...

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Bibliographic Details
Main Authors: Aleksandra Agafonova, Alessia Cosentino, Ivana Roberta Romano, Giovanni Giurdanella, Floriana D’Angeli, Rosario Giuffrida, Debora Lo Furno, Carmelina Daniela Anfuso, Giuliana Mannino, Gabriella Lupo
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
adipose mesenchymal stem cells
pericyte-like differentiation
human retinal endothelial cells
blood–retinal barrier
diabetic retinopathy
hyperglycemia
Online Access:https://www.mdpi.com/1422-0067/25/3/1774

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https://www.mdpi.com/1422-0067/25/3/1774

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