Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice
Background and Objective: The increasing usage of cell phones, have raised concerns about the potential effects of these waves on the health of individuals. In the present research the effect of mobile phone radiation on the expression of DAZL gene in BALB/c mice were studied. Methods: 18 male mice...
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| Format: | Article |
| Language: | fas |
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Golestan University of Medical Sciences
2021-01-01
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| Series: | مجله دانشگاه علوم پزشکی گرگان |
| Subjects: | |
| Online Access: | http://goums.ac.ir/journal/article-1-3650-en.html |
| _version_ | 1818873471221891072 |
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| author | Mahshid Golkar Moghaddam Saeedeh Zafar Balanejad Jina Khayatzadeh |
| author_facet | Mahshid Golkar Moghaddam Saeedeh Zafar Balanejad Jina Khayatzadeh |
| author_sort | Mahshid Golkar Moghaddam |
| collection | DOAJ |
| description | Background and Objective: The increasing usage of cell phones, have raised concerns about the potential effects of these waves on the health of individuals. In the present research the effect of mobile phone radiation on the expression of DAZL gene in BALB/c mice were studied.
Methods: 18 male mice were divided into three groups: Control, sham-exposed and experimental. Experimental mice were exposed to mobile waves for 2 hours daily, during 3 weeks. After 3 weeks, the testes were excised and RNA extraction and Real-Time PCR were performed. Sperm counts in deferen channel and the study of sperm motility in epididymis were done.
Results: The percentage of non-progressive sperm motility significantly increased in experimental group in compared to control group (P<0.05).The level of DAZL gene expression in the experimental group was significantly lower than the control group (P<0.05). Weight of the testis, percentage of live sperm, percentage of rapid progressive sperm motility and percentage of slow progressive sperm motility non-significantly reduced in experimental group in comparison with controls.
Conclusion: Exposure to cell phone waves for 21 days and 2 hours a day impairs spermatogenesis by reducing the quality and motility of sperm and also reduction of expression of DAZL gene. |
| first_indexed | 2024-12-19T12:55:14Z |
| format | Article |
| id | doaj.art-ea8c02dac7f649ff9f38cecacd92f2f4 |
| institution | Directory Open Access Journal |
| issn | 1562-4765 2008-4080 |
| language | fas |
| last_indexed | 2024-12-19T12:55:14Z |
| publishDate | 2021-01-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشگاه علوم پزشکی گرگان |
| spelling | doaj.art-ea8c02dac7f649ff9f38cecacd92f2f42022-12-21T20:20:25ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802021-01-012246369Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c miceMahshid Golkar Moghaddam0Saeedeh Zafar Balanejad1Jina Khayatzadeh2 M.Sc in Genetics, Department of Biology, Faculty of Basic Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran. Assistant Professor, Department of Biology, Faculty of Basic Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran. Assistant Professor, Department of Biology, Faculty of Basic Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran. Background and Objective: The increasing usage of cell phones, have raised concerns about the potential effects of these waves on the health of individuals. In the present research the effect of mobile phone radiation on the expression of DAZL gene in BALB/c mice were studied. Methods: 18 male mice were divided into three groups: Control, sham-exposed and experimental. Experimental mice were exposed to mobile waves for 2 hours daily, during 3 weeks. After 3 weeks, the testes were excised and RNA extraction and Real-Time PCR were performed. Sperm counts in deferen channel and the study of sperm motility in epididymis were done. Results: The percentage of non-progressive sperm motility significantly increased in experimental group in compared to control group (P<0.05).The level of DAZL gene expression in the experimental group was significantly lower than the control group (P<0.05). Weight of the testis, percentage of live sperm, percentage of rapid progressive sperm motility and percentage of slow progressive sperm motility non-significantly reduced in experimental group in comparison with controls. Conclusion: Exposure to cell phone waves for 21 days and 2 hours a day impairs spermatogenesis by reducing the quality and motility of sperm and also reduction of expression of DAZL gene.http://goums.ac.ir/journal/article-1-3650-en.htmlinfertilitycell phonedazl gene |
| spellingShingle | Mahshid Golkar Moghaddam Saeedeh Zafar Balanejad Jina Khayatzadeh Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice مجله دانشگاه علوم پزشکی گرگان infertility cell phone dazl gene |
| title | Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice |
| title_full | Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice |
| title_fullStr | Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice |
| title_full_unstemmed | Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice |
| title_short | Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice |
| title_sort | effect of cell phone radiation on sperm characteristics and dazl gene expression in balb c mice |
| topic | infertility cell phone dazl gene |
| url | http://goums.ac.ir/journal/article-1-3650-en.html |
| work_keys_str_mv | AT mahshidgolkarmoghaddam effectofcellphoneradiationonspermcharacteristicsanddazlgeneexpressioninbalbcmice AT saeedehzafarbalanejad effectofcellphoneradiationonspermcharacteristicsanddazlgeneexpressioninbalbcmice AT jinakhayatzadeh effectofcellphoneradiationonspermcharacteristicsanddazlgeneexpressioninbalbcmice |