Antimicrobial and Resistance Modulatory Activity of Alpinia katsumadai Seed Phenolic Extract, Essential Oil and Post-Distillation Extract
Antimicrobial resistance of food-related bacterial pathogens is becoming a serious problem, especially after the emergence of multidrug-resistant strains. To overcome this problem, new and effective antimicrobials or resistance modulators are highly needed and plant kingdom represents a valuable sou...
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| Format: | Article |
| Language: | English |
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University of Zagreb Faculty of Food Technology and Biotechnology
2014-01-01
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| Series: | Food Technology and Biotechnology |
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| Online Access: | http://hrcak.srce.hr/file/180895 |
| _version_ | 1827608695769399296 |
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| author | Jasna Kovač Neda Gavarić Franz Bucar Sonja Smole Možina |
| author_facet | Jasna Kovač Neda Gavarić Franz Bucar Sonja Smole Možina |
| author_sort | Jasna Kovač |
| collection | DOAJ |
| description | Antimicrobial resistance of food-related bacterial pathogens is becoming a serious problem, especially after the emergence of multidrug-resistant strains. To overcome this problem, new and effective antimicrobials or resistance modulators are highly needed and plant kingdom represents a valuable source of these compounds. We investigated antimicrobial and resistance modulatory activity of the phenolic extract, essential oil and post-distillation extract of Alpinia katsumadai seeds against Campylobacter jejuni and Staphylococcus aureus. Among the tested plant formulations, A. katsumadai seed phenolic extract and post-distillation extract showed moderate antimicrobial activity against C. jejuni, while S. aureus was more resistant. When evaluating resistance modulatory potential of A. katsumadai phenolic extract, essential oil and post-distillation extract in C. jejuni against ciprofloxacin, erythromycin, triclosan, bile salts and ethidium bromide, plant formulations exhibited modulatory activity in combination with all antimicrobials. Modulation of resistance was more strain- and antimicrobial-specific in S. aureus, but very efficient in the case of reduced resistance to bile salts. Essential oil from A. katsumadai seeds efficiently increased intracellular ethidium bromide accumulation and was thus confirmed as potential inhibitor of efflux pumps in C. jejuni and S. aureus. |
| first_indexed | 2024-03-09T07:18:21Z |
| format | Article |
| id | doaj.art-ea90b3f77a994d68953b2ba16d7a3198 |
| institution | Directory Open Access Journal |
| issn | 1330-9862 1334-2606 |
| language | English |
| last_indexed | 2024-03-09T07:18:21Z |
| publishDate | 2014-01-01 |
| publisher | University of Zagreb Faculty of Food Technology and Biotechnology |
| record_format | Article |
| series | Food Technology and Biotechnology |
| spelling | doaj.art-ea90b3f77a994d68953b2ba16d7a31982023-12-03T08:16:29ZengUniversity of Zagreb Faculty of Food Technology and BiotechnologyFood Technology and Biotechnology1330-98621334-26062014-01-01522248254Antimicrobial and Resistance Modulatory Activity of Alpinia katsumadai Seed Phenolic Extract, Essential Oil and Post-Distillation ExtractJasna Kovač0Neda Gavarić1Franz Bucar2Sonja Smole Možina3Department of Food Science and Technology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, SloveniaDepartment of Pharmacy, Medical Faculty, University of Novi Sad, Hajduk Veljkova 3, RS-21000 Novi Sad, SerbiaInstitute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz, Universitätsplatz 4, AT-8010 Graz, AustriaDepartment of Food Science and Technology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, SloveniaAntimicrobial resistance of food-related bacterial pathogens is becoming a serious problem, especially after the emergence of multidrug-resistant strains. To overcome this problem, new and effective antimicrobials or resistance modulators are highly needed and plant kingdom represents a valuable source of these compounds. We investigated antimicrobial and resistance modulatory activity of the phenolic extract, essential oil and post-distillation extract of Alpinia katsumadai seeds against Campylobacter jejuni and Staphylococcus aureus. Among the tested plant formulations, A. katsumadai seed phenolic extract and post-distillation extract showed moderate antimicrobial activity against C. jejuni, while S. aureus was more resistant. When evaluating resistance modulatory potential of A. katsumadai phenolic extract, essential oil and post-distillation extract in C. jejuni against ciprofloxacin, erythromycin, triclosan, bile salts and ethidium bromide, plant formulations exhibited modulatory activity in combination with all antimicrobials. Modulation of resistance was more strain- and antimicrobial-specific in S. aureus, but very efficient in the case of reduced resistance to bile salts. Essential oil from A. katsumadai seeds efficiently increased intracellular ethidium bromide accumulation and was thus confirmed as potential inhibitor of efflux pumps in C. jejuni and S. aureus.http://hrcak.srce.hr/file/180895antimicrobial activityantimicrobial resistanceresistance modulationAlpinia katsumadai seed extractsessential oilefflux inhibition |
| spellingShingle | Jasna Kovač Neda Gavarić Franz Bucar Sonja Smole Možina Antimicrobial and Resistance Modulatory Activity of Alpinia katsumadai Seed Phenolic Extract, Essential Oil and Post-Distillation Extract Food Technology and Biotechnology antimicrobial activity antimicrobial resistance resistance modulation Alpinia katsumadai seed extracts essential oil efflux inhibition |
| title | Antimicrobial and Resistance Modulatory Activity of Alpinia katsumadai Seed Phenolic Extract, Essential Oil and Post-Distillation Extract |
| title_full | Antimicrobial and Resistance Modulatory Activity of Alpinia katsumadai Seed Phenolic Extract, Essential Oil and Post-Distillation Extract |
| title_fullStr | Antimicrobial and Resistance Modulatory Activity of Alpinia katsumadai Seed Phenolic Extract, Essential Oil and Post-Distillation Extract |
| title_full_unstemmed | Antimicrobial and Resistance Modulatory Activity of Alpinia katsumadai Seed Phenolic Extract, Essential Oil and Post-Distillation Extract |
| title_short | Antimicrobial and Resistance Modulatory Activity of Alpinia katsumadai Seed Phenolic Extract, Essential Oil and Post-Distillation Extract |
| title_sort | antimicrobial and resistance modulatory activity of alpinia katsumadai seed phenolic extract essential oil and post distillation extract |
| topic | antimicrobial activity antimicrobial resistance resistance modulation Alpinia katsumadai seed extracts essential oil efflux inhibition |
| url | http://hrcak.srce.hr/file/180895 |
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