Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia
Background: To assess the effects of Rocuronium pretreatment on Succinylcholine induced rise in serum potassium. Methods: In this randomized controlled experimental study, sixty adults ASA I or II patients who presented for elective general surgical procedures were included. The patients were divide...
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| Format: | Article |
| Language: | English |
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Rawalpindi Medical University
2012-12-01
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| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/571 |
| _version_ | 1818107997777297408 |
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| author | Kulsoom Farhat |
| author_facet | Kulsoom Farhat |
| author_sort | Kulsoom Farhat |
| collection | DOAJ |
| description | Background: To assess the effects of Rocuronium
pretreatment on Succinylcholine induced rise in serum
potassium.
Methods: In this randomized controlled experimental
study, sixty adults ASA I or II patients who presented for
elective general surgical procedures were included. The
patients were divided in two groups of thirty each by a
simple randomization. Group "A" received succinylcholine
and group "B" received precurarization dose of rocuronium
followed by succinylcholine for intubation. Venous blood
samples were obtained for estimation of serum potassium
(K+) at 0 minutes and after five minutes of intubation.
Results: There was a significant rise in serum K+ level
from the start of the study to five minutes in group A (p <
0.001). In group B, increase in serum K+ level from start of
the study to five minutes was significant (p = 0.001) but it
remained within the normal range. The increase in serum
K+ level was significantly more in group A as compared to
group B (p < 0.001).
Conclusion: Pretreatment with rocuronium prevents
the rise in serum potassium induced by succinylcholine |
| first_indexed | 2024-12-11T02:08:21Z |
| format | Article |
| id | doaj.art-ea913d65208640b8b7291a29901b1df1 |
| institution | Directory Open Access Journal |
| issn | 1683-3562 1683-3570 |
| language | English |
| last_indexed | 2024-12-11T02:08:21Z |
| publishDate | 2012-12-01 |
| publisher | Rawalpindi Medical University |
| record_format | Article |
| series | Journal of Rawalpindi Medical College |
| spelling | doaj.art-ea913d65208640b8b7291a29901b1df12022-12-22T01:24:20ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702012-12-01162Precurarization with Rocuronium Prevents Succinylcholine induced HyperkalemiaKulsoom Farhat0Department of Pharmacology, Army Medical College, RawalpindiBackground: To assess the effects of Rocuronium pretreatment on Succinylcholine induced rise in serum potassium. Methods: In this randomized controlled experimental study, sixty adults ASA I or II patients who presented for elective general surgical procedures were included. The patients were divided in two groups of thirty each by a simple randomization. Group "A" received succinylcholine and group "B" received precurarization dose of rocuronium followed by succinylcholine for intubation. Venous blood samples were obtained for estimation of serum potassium (K+) at 0 minutes and after five minutes of intubation. Results: There was a significant rise in serum K+ level from the start of the study to five minutes in group A (p < 0.001). In group B, increase in serum K+ level from start of the study to five minutes was significant (p = 0.001) but it remained within the normal range. The increase in serum K+ level was significantly more in group A as compared to group B (p < 0.001). Conclusion: Pretreatment with rocuronium prevents the rise in serum potassium induced by succinylcholinehttps://www.journalrmc.com/index.php/JRMC/article/view/571SuccinylcholineRocuronium,Potassium,Precurarization |
| spellingShingle | Kulsoom Farhat Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia Journal of Rawalpindi Medical College Succinylcholine Rocuronium, Potassium, Precurarization |
| title | Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia |
| title_full | Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia |
| title_fullStr | Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia |
| title_full_unstemmed | Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia |
| title_short | Precurarization with Rocuronium Prevents Succinylcholine induced Hyperkalemia |
| title_sort | precurarization with rocuronium prevents succinylcholine induced hyperkalemia |
| topic | Succinylcholine Rocuronium, Potassium, Precurarization |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/571 |
| work_keys_str_mv | AT kulsoomfarhat precurarizationwithrocuroniumpreventssuccinylcholineinducedhyperkalemia |