Eosinophilic gastroenteritis following COVID-19 mRNA vaccination

Introduction: Large-scale clinical studies for COVID-19 vaccines have shown the infection-preventing effect and short-term adverse effects. Some rare illnesses such as eosinophilia can develop following COVID-19 vaccinations. Case description: We report a case of 65-year-old man with unexplained abd...

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Bibliographic Details
Main Authors: Yuta Yoshino, Ken Tsuboi
Format: Article
Language:English
Published: SMC MEDIA SRL 2024-02-01
Series:European Journal of Case Reports in Internal Medicine
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/4316
Description
Summary:Introduction: Large-scale clinical studies for COVID-19 vaccines have shown the infection-preventing effect and short-term adverse effects. Some rare illnesses such as eosinophilia can develop following COVID-19 vaccinations. Case description: We report a case of 65-year-old man with unexplained abdominal pain that developed 2 weeks after COVID-19 mRNA vaccination. The patient had received a second dose of COVID-19 mRNA vaccine and revealed eosinophilia at the first visit to our hospital. Eosinophil infiltration was observed in the lamina propria of the duodenum by a step biopsy. Montelukast 10 mg was administered as the initial treatment of eosinophilic gastroenteritis (EGE), and the abdominal pain was improved. Discussion: The strong influence of COVID-19 vaccination on the development of EGE remains unproven. Reports of eosinophilia following COVID-19 vaccination have discussed that COVID-19 mRNA vaccination triggered an eosinophilic response. Conclusion: This case presented EGE that developed following COVID-19 mRNA vaccination, which would be a rare adverse event.
ISSN:2284-2594