Association between megakaryocyte abnormalities on bone marrow smear and response to thrombopoietin receptor agonists in adult patients with primary immune thrombocytopenia

Association between megakaryocyte abnormalities on bone marrow smear and response to thrombopoietin receptor agonists in adult patients with primary immune thrombocytopenia

Impaired platelet production is a mechanism of immune thrombocytopenia (ITP). Morphological abnormalities of megakaryocytes (MKs) are sometimes observed in this disease. Two studies have suggested an association between MK abnormalities and response to corticosteroids in primary ITP, but none have i...

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Bibliographic Details
Main Authors: Ondine Walter, Agnès Ribes, Johanne Germain, Jean-Baptiste Rieu, Thibaut Comont, Albertine Plat, Brigitte Rivière, Laureline Deluche, Lucrecia Delarue, Isabelle LeGoff, Monique Greze, Béatrice Dubourdieu, Odile Rauzy, Veronique Mansat-De Mas, Guillaume Moulis, the CARMEN investigators group.
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Platelets
Subjects:
immune thrombocytopenia
megakaryocytes
thrombopoietin receptor agonist
Online Access:http://dx.doi.org/10.1080/09537104.2022.2053089

Internet

http://dx.doi.org/10.1080/09537104.2022.2053089

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