Synthesis and Antiviral Evaluation of Nucleoside Analogues Bearing One Pyrimidine Moiety and Two D-Ribofuranosyl Residues

Synthesis and Antiviral Evaluation of Nucleoside Analogues Bearing One Pyrimidine Moiety and Two D-Ribofuranosyl Residues

A series of 1,2,3-triazolyl nucleoside analogues in which 1,2,3-triazol-4-yl-β-<span style="font-variant: small-caps;">d</span>-ribofuranosyl fragments are attached via polymethylene linkers to both nitrogen atoms of the heterocycle moiety (uracil, 6-methyluracil, thymine, quin...

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Bibliographic Details
Main Authors: Olga V. Andreeva, Bulat F. Garifullin, Vladimir V. Zarubaev, Alexander V. Slita, Iana L. Yesaulkova, Alexandrina S. Volobueva, Mayya G. Belenok, Maria A. Man’kova, Liliya F. Saifina, Marina M. Shulaeva, Alexandra D. Voloshina, Anna P. Lyubina, Vyacheslav E. Semenov, Vladimir E. Kataev
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
nucleoside analogues
antivirals
1,2,3-triazole
influenza virus
coxsackievirus
click chemistry
Online Access:https://www.mdpi.com/1420-3049/26/12/3678

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