TeratoScore: Assessing the Differentiation Potential of Human Pluripotent Stem Cells by Quantitative Expression Analysis of Teratomas
Teratoma formation is the gold standard assay for testing the capacity of human pluripotent stem cells to differentiate into all embryonic germ layers. Although widely used, little effort has been made to transform this qualitative assay into a quantitative one. Using gene expression data from a wid...
Main Authors: | Yishai Avior, Juan Carlos Biancotti, Nissim Benvenisty |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2015-06-01
|
Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671115001496 |
Similar Items
-
Modeling Developmental and Tumorigenic Aspects of Trilateral Retinoblastoma via Human Embryonic Stem Cells
by: Yishai Avior, et al.
Published: (2017-05-01) -
Sex-Dependent Gene Expression in Human Pluripotent Stem Cells
by: Daniel Ronen, et al.
Published: (2014-08-01) -
Molecular Characterization of Down Syndrome Embryonic Stem Cells Reveals a Role for RUNX1 in Neural Differentiation
by: Tomer Halevy, et al.
Published: (2016-10-01) -
Modeling Maturity Onset Diabetes of the Young in Pluripotent Stem Cells: Challenges and Achievements
by: Carmel Braverman-Gross, et al.
Published: (2021-02-01) -
Murine pluripotent stem cells that escape differentiation inside teratomas maintain pluripotency
by: Yangli Pei, et al.
Published: (2018-01-01)