Does the mouse tail vein injection method provide a good model of lung cancer? [version 1; peer review: 2 approved]

Does the mouse tail vein injection method provide a good model of lung cancer? [version 1; peer review: 2 approved]

Lung cancer drug development requires screening in animal models. We aimed to develop orthotopic models of human non-small lung cancer using A549 and H3122 cells delivered by tail vein injection. This procedure has been used previously for a mouse lung cancer (Lewis lung carcinoma) and as a model of...

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Bibliographic Details
Main Authors:	Nensi Shrestha, Zabeen Lateef, Orleans Martey, Abigail R. Bland, Mhairi Nimick, Rhonda Rosengren, John C. Ashton
Format:	Article
Language:	English
Published:	F1000 Research Ltd 2019-02-01
Series:	F1000Research
Online Access:	https://f1000research.com/articles/8-190/v1

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