Extrinsic Adenomyosis Is Associated With Postoperative Recurrence of Ovarian Endometrioma
Objective: To determine whether endometrioma recurrence is closely related to the presence of extrinsic adenomyosis, which was demonstrated by magnetic resonance imaging (MRI).Design: Observational crosssectional study involving patients with the recurrence of ovarian endometrioma (OMA). Correlation...
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Frontiers Media S.A.
2022-01-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2021.815628/full |
| _version_ | 1819282362161168384 |
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| author | Man Sun Ping Xu Gen Zou Jianzhang Wang Libo Zhu Xinmei Zhang |
| author_facet | Man Sun Ping Xu Gen Zou Jianzhang Wang Libo Zhu Xinmei Zhang |
| author_sort | Man Sun |
| collection | DOAJ |
| description | Objective: To determine whether endometrioma recurrence is closely related to the presence of extrinsic adenomyosis, which was demonstrated by magnetic resonance imaging (MRI).Design: Observational crosssectional study involving patients with the recurrence of ovarian endometrioma (OMA). Correlations of endometrioma recurrence and adenomyosis subtypes shown by MRI were analyzed.Method: Between January 2018 and December 2020, a total of 233 patients with recurrence of OMA after ovarian cystectomy were administered for surgery at our institution. All patients were divided into subtype II (Group A), subtype I+IV (Group B), and nonadenomyosis (Group C) groups at preoperative MRI imaging. The correlations of endometrioma recurrence with clinical features, imaging appearance, and surgical findings were retrospectively analyzed.Results: We found 112 (48.07%) patients of endometrioma recurrence combined with subtype II adenomyosis, 8 (3.43%) subtype I adenomyosis, 47 (20.17%) subtype IV adenomyosis, 66 (28.32%) nonadenomyosis. The mean time of OMA recurrence (44.28 ± 8.37, vs. 63.96 ± 10.28, vs. 69.36 ± 9.34 mon), rate of pain symptoms (85.71, vs. 69.10, vs. 18.18%), and primary infertility (31.25, vs. 14.55, vs. 10.77%) were higher in Group A. Uterine volume (257.37± 42.61, vs. 203.14 ± 33.52, vs. 100.85 ± 26.67 cm3), and mean OMA size (4.97 ± 2.25, vs. 4.36 ± 2.38, vs. 4.46 ± 2.70 cm) were significantly larger in Group A. The rate of DIE (83.93, vs. 45.45, vs. 40.91%), the number of DIE (3.6 ± 1.8 vs. 2.3 ± 1.5 vs. 2.2 ± 1.3), the mean total revised American Society for Reproductive Medicine score (rASRM, 103.14 ± 23.89 vs. 74.23 ± 16.72 vs. 36.51 ± 14.23) were significantly higher in Group A. After a multiple logistic regression analysis, extrinsic adenomyosis (OR 2.5, 95% CI 1.2–3.4), DIE lesions (OR 2.1, 95% CI 1.4–2.8), and primary infertility (OR 1.8, 95% CI 1.3–4.3) were significantly associated with early recurrence (in 3-year) of OMA.Conclusions: Extrinsic adenomyosis was associated with postoperative recurrence of OMA. In addition, a pathogenic link between extrinsic adenomyosis and pelvic endometriosis needs to be clarified. |
| first_indexed | 2024-12-24T01:14:23Z |
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| language | English |
| last_indexed | 2024-12-24T01:14:23Z |
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| spelling | doaj.art-ea9dbadacdb643a88dbe39afcffe82802022-12-21T17:22:48ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-01-01810.3389/fmed.2021.815628815628Extrinsic Adenomyosis Is Associated With Postoperative Recurrence of Ovarian EndometriomaMan SunPing XuGen ZouJianzhang WangLibo ZhuXinmei ZhangObjective: To determine whether endometrioma recurrence is closely related to the presence of extrinsic adenomyosis, which was demonstrated by magnetic resonance imaging (MRI).Design: Observational crosssectional study involving patients with the recurrence of ovarian endometrioma (OMA). Correlations of endometrioma recurrence and adenomyosis subtypes shown by MRI were analyzed.Method: Between January 2018 and December 2020, a total of 233 patients with recurrence of OMA after ovarian cystectomy were administered for surgery at our institution. All patients were divided into subtype II (Group A), subtype I+IV (Group B), and nonadenomyosis (Group C) groups at preoperative MRI imaging. The correlations of endometrioma recurrence with clinical features, imaging appearance, and surgical findings were retrospectively analyzed.Results: We found 112 (48.07%) patients of endometrioma recurrence combined with subtype II adenomyosis, 8 (3.43%) subtype I adenomyosis, 47 (20.17%) subtype IV adenomyosis, 66 (28.32%) nonadenomyosis. The mean time of OMA recurrence (44.28 ± 8.37, vs. 63.96 ± 10.28, vs. 69.36 ± 9.34 mon), rate of pain symptoms (85.71, vs. 69.10, vs. 18.18%), and primary infertility (31.25, vs. 14.55, vs. 10.77%) were higher in Group A. Uterine volume (257.37± 42.61, vs. 203.14 ± 33.52, vs. 100.85 ± 26.67 cm3), and mean OMA size (4.97 ± 2.25, vs. 4.36 ± 2.38, vs. 4.46 ± 2.70 cm) were significantly larger in Group A. The rate of DIE (83.93, vs. 45.45, vs. 40.91%), the number of DIE (3.6 ± 1.8 vs. 2.3 ± 1.5 vs. 2.2 ± 1.3), the mean total revised American Society for Reproductive Medicine score (rASRM, 103.14 ± 23.89 vs. 74.23 ± 16.72 vs. 36.51 ± 14.23) were significantly higher in Group A. After a multiple logistic regression analysis, extrinsic adenomyosis (OR 2.5, 95% CI 1.2–3.4), DIE lesions (OR 2.1, 95% CI 1.4–2.8), and primary infertility (OR 1.8, 95% CI 1.3–4.3) were significantly associated with early recurrence (in 3-year) of OMA.Conclusions: Extrinsic adenomyosis was associated with postoperative recurrence of OMA. In addition, a pathogenic link between extrinsic adenomyosis and pelvic endometriosis needs to be clarified.https://www.frontiersin.org/articles/10.3389/fmed.2021.815628/fullovarian endometriomarecurrenceextrinsic adenomyosisDIEprimary fertility |
| spellingShingle | Man Sun Ping Xu Gen Zou Jianzhang Wang Libo Zhu Xinmei Zhang Extrinsic Adenomyosis Is Associated With Postoperative Recurrence of Ovarian Endometrioma Frontiers in Medicine ovarian endometrioma recurrence extrinsic adenomyosis DIE primary fertility |
| title | Extrinsic Adenomyosis Is Associated With Postoperative Recurrence of Ovarian Endometrioma |
| title_full | Extrinsic Adenomyosis Is Associated With Postoperative Recurrence of Ovarian Endometrioma |
| title_fullStr | Extrinsic Adenomyosis Is Associated With Postoperative Recurrence of Ovarian Endometrioma |
| title_full_unstemmed | Extrinsic Adenomyosis Is Associated With Postoperative Recurrence of Ovarian Endometrioma |
| title_short | Extrinsic Adenomyosis Is Associated With Postoperative Recurrence of Ovarian Endometrioma |
| title_sort | extrinsic adenomyosis is associated with postoperative recurrence of ovarian endometrioma |
| topic | ovarian endometrioma recurrence extrinsic adenomyosis DIE primary fertility |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2021.815628/full |
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