Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma
The main symptoms of adenomyosis may adversely affect physical and mental health and quality of life (QOL). However, studies are few on this topic. This study evaluated the effect of adenomyosis on anxiety, depression, and QOL. Participants with adenomyosis (<i>n</i> = 90) or leiomyoma (...
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MDPI AG
2022-05-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/9/2638 |
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| author | Ni Li Ming Yuan Qiuju Li Miaomiao Ji Xue Jiao Guoyun Wang |
| author_facet | Ni Li Ming Yuan Qiuju Li Miaomiao Ji Xue Jiao Guoyun Wang |
| author_sort | Ni Li |
| collection | DOAJ |
| description | The main symptoms of adenomyosis may adversely affect physical and mental health and quality of life (QOL). However, studies are few on this topic. This study evaluated the effect of adenomyosis on anxiety, depression, and QOL. Participants with adenomyosis (<i>n</i> = 90) or leiomyoma (<i>n</i> = 59) completed questionnaires, including the visual analog scale (VAS) for pain, Hospital Anxiety and Depression Scale (HADS), and Short Form (SF)-36. HADS anxiety and depression positive rates, physical (PCS) and mental (MCS) component summary scores, and eight subscale scores of SF-36 were compared between the two groups. Among patients with adenomyosis, the incidence of anxiety symptoms was 28.9% (control group, 10.2%; OR = 3.589, 95% CI: 1.375–9.367), with 10% of patients showing moderate-to-severe symptoms. The incidence of depressive symptoms was 14.4% (control group, 3.4%; OR = 4.812, 95% CI: 1.044–22.168). The case group had significantly lower PCS and MCS scores than the control group. In patients with adenomyosis, being employed (OR = 6.393, 95% CI: 1.153–35.440) and perianal pain (OR = 25.419, 95% CI: 2.504–258.024) were risk factors for anxiety, and perianal pain (OR = 15.208, 95% CI: 3.050–75.836) was a risk factor for depression. Compared with leiomyoma, adenomyosis is associated with a higher risk of anxiety and depression, with a poorer QOL. |
| first_indexed | 2024-03-10T04:00:56Z |
| format | Article |
| id | doaj.art-ea9e61db4f474d6abfa587b9fad206fa |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T04:00:56Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-ea9e61db4f474d6abfa587b9fad206fa2023-11-23T08:35:17ZengMDPI AGJournal of Clinical Medicine2077-03832022-05-01119263810.3390/jcm11092638Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine LeiomyomaNi Li0Ming Yuan1Qiuju Li2Miaomiao Ji3Xue Jiao4Guoyun Wang5Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, ChinaDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, ChinaDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, ChinaDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, ChinaDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, ChinaDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, ChinaThe main symptoms of adenomyosis may adversely affect physical and mental health and quality of life (QOL). However, studies are few on this topic. This study evaluated the effect of adenomyosis on anxiety, depression, and QOL. Participants with adenomyosis (<i>n</i> = 90) or leiomyoma (<i>n</i> = 59) completed questionnaires, including the visual analog scale (VAS) for pain, Hospital Anxiety and Depression Scale (HADS), and Short Form (SF)-36. HADS anxiety and depression positive rates, physical (PCS) and mental (MCS) component summary scores, and eight subscale scores of SF-36 were compared between the two groups. Among patients with adenomyosis, the incidence of anxiety symptoms was 28.9% (control group, 10.2%; OR = 3.589, 95% CI: 1.375–9.367), with 10% of patients showing moderate-to-severe symptoms. The incidence of depressive symptoms was 14.4% (control group, 3.4%; OR = 4.812, 95% CI: 1.044–22.168). The case group had significantly lower PCS and MCS scores than the control group. In patients with adenomyosis, being employed (OR = 6.393, 95% CI: 1.153–35.440) and perianal pain (OR = 25.419, 95% CI: 2.504–258.024) were risk factors for anxiety, and perianal pain (OR = 15.208, 95% CI: 3.050–75.836) was a risk factor for depression. Compared with leiomyoma, adenomyosis is associated with a higher risk of anxiety and depression, with a poorer QOL.https://www.mdpi.com/2077-0383/11/9/2638adenomyosisanxietydepressionquality of life |
| spellingShingle | Ni Li Ming Yuan Qiuju Li Miaomiao Ji Xue Jiao Guoyun Wang Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma Journal of Clinical Medicine adenomyosis anxiety depression quality of life |
| title | Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma |
| title_full | Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma |
| title_fullStr | Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma |
| title_full_unstemmed | Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma |
| title_short | Higher Risk of Anxiety and Depression in Women with Adenomyosis as Compared with Those with Uterine Leiomyoma |
| title_sort | higher risk of anxiety and depression in women with adenomyosis as compared with those with uterine leiomyoma |
| topic | adenomyosis anxiety depression quality of life |
| url | https://www.mdpi.com/2077-0383/11/9/2638 |
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