Food Allergies - Trends and Challenges in Treatment and Diagnosis
Introduction: Food allergies are becoming an increasingly significant challenge for medicine, public health and patients' quality of life. Over the past few decades, there has been an observed increase in the number of cases of food allergies. This has led to h...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2023-09-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/45615 |
| _version_ | 1827822061000589312 |
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| author | Zuzanna Sawińska Katarzyna Sudelska Grzegorz Tarsa Przemysław Kępka Aleksandra Łokczewska-Bojar Magdalena Skotalczyk Daria Kuziemkowska Jan Kużma Rami Ben Rhaiem Anna Łącka-Majcher |
| author_facet | Zuzanna Sawińska Katarzyna Sudelska Grzegorz Tarsa Przemysław Kępka Aleksandra Łokczewska-Bojar Magdalena Skotalczyk Daria Kuziemkowska Jan Kużma Rami Ben Rhaiem Anna Łącka-Majcher |
| author_sort | Zuzanna Sawińska |
| collection | DOAJ |
| description |
Introduction:
Food allergies are becoming an increasingly significant challenge for medicine, public health and patients' quality of life. Over the past few decades, there has been an observed increase in the number of cases of food allergies. This has led to heightened interest among scientists, doctors and specialists in various aspects related to the diagnosis and treatment of this condition. With the increasing precision of food allergy diagnosis, it is necessary to adjust the therapy to the individual needs of patients.
Aim of the study:
The aim of our study is to summarize the trends and challenges in treatment and diagnosis of food allergies. We focused on current diagnostic methods and treatment options, as well as
new promising therapeutic approaches.
State of knowledge:
In molecular or component-resolved diagnostic tests (CRD), specific IgE antibodies are measured for individual food allergenic molecules. This presents an opportunity to improve specificity for selected foods. Studies have shown that the Basophil Activation Test (BAT) exhibits higher specificity than skin prick tests (SPT) and s-IgE tests, while maintaining its sensitivity. BAT relies on flow cytometry, where the expression of activation markers on the surface of basophils stimulated by an antigen is measured.
Due to the existing limitations of certain tests, Oral Food Challenge (OFC) is still considered the gold standard for diagnosing IgE-mediated food allergies.
Summary:
Research shows that the foundation of diagnosis is the patient's medical history, including a properly collected interview, which should then guide the doctor towards appropriate tests.
An elimination diet based on the clinical interview should be implemented until significant relief of allergy symptoms is achieved.
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| first_indexed | 2024-03-12T01:52:47Z |
| format | Article |
| id | doaj.art-ea9fa7f600ed4828b6017a5ddbdeb970 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-12T01:52:47Z |
| publishDate | 2023-09-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-ea9fa7f600ed4828b6017a5ddbdeb9702023-09-08T10:48:54ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-09-0116110.12775/JEHS.2023.16.01.017Food Allergies - Trends and Challenges in Treatment and DiagnosisZuzanna Sawińska0Katarzyna Sudelska1Grzegorz Tarsa2Przemysław Kępka3Aleksandra Łokczewska-Bojar4Magdalena Skotalczyk5Daria Kuziemkowska6Jan Kużma7Rami Ben Rhaiem8Anna Łącka-Majcher9Śląski Uniwersytet Medyczny w Katowicach Śląski Uniwersytet Medyczny w KatowicachBonifraterskie Centrum Medyczne sp. zooSzpital Wojewódzki w Bielsku-BiałejSzpital Specjalistyczny im. Jędrzeja Śniadeckiego w Nowym SączuUniwersyteckie Centrum Kliniczne im. prof. K. Gibińskiego Śląskiego Uniwersytetu Medycznego w KatowicachSP ZOZ MSWiA w Katowicach im. Sierżanta Grzegorza ZałogiGórnośląskie Centrum Medyczne im. Prof. L. Gieca w KatowicachSamodzielny Publiczny Zespół Opieki Zdrowotnej w Kędzierzynie-KoźluSamodzielny Publiczny Zakład Opieki Zdrowotnej w Bochni Introduction: Food allergies are becoming an increasingly significant challenge for medicine, public health and patients' quality of life. Over the past few decades, there has been an observed increase in the number of cases of food allergies. This has led to heightened interest among scientists, doctors and specialists in various aspects related to the diagnosis and treatment of this condition. With the increasing precision of food allergy diagnosis, it is necessary to adjust the therapy to the individual needs of patients. Aim of the study: The aim of our study is to summarize the trends and challenges in treatment and diagnosis of food allergies. We focused on current diagnostic methods and treatment options, as well as new promising therapeutic approaches. State of knowledge: In molecular or component-resolved diagnostic tests (CRD), specific IgE antibodies are measured for individual food allergenic molecules. This presents an opportunity to improve specificity for selected foods. Studies have shown that the Basophil Activation Test (BAT) exhibits higher specificity than skin prick tests (SPT) and s-IgE tests, while maintaining its sensitivity. BAT relies on flow cytometry, where the expression of activation markers on the surface of basophils stimulated by an antigen is measured. Due to the existing limitations of certain tests, Oral Food Challenge (OFC) is still considered the gold standard for diagnosing IgE-mediated food allergies. Summary: Research shows that the foundation of diagnosis is the patient's medical history, including a properly collected interview, which should then guide the doctor towards appropriate tests. An elimination diet based on the clinical interview should be implemented until significant relief of allergy symptoms is achieved. https://apcz.umk.pl/JEHS/article/view/45615food allergyBasophil Degranulation Testmilk allergypeanut allergy |
| spellingShingle | Zuzanna Sawińska Katarzyna Sudelska Grzegorz Tarsa Przemysław Kępka Aleksandra Łokczewska-Bojar Magdalena Skotalczyk Daria Kuziemkowska Jan Kużma Rami Ben Rhaiem Anna Łącka-Majcher Food Allergies - Trends and Challenges in Treatment and Diagnosis Journal of Education, Health and Sport food allergy Basophil Degranulation Test milk allergy peanut allergy |
| title | Food Allergies - Trends and Challenges in Treatment and Diagnosis |
| title_full | Food Allergies - Trends and Challenges in Treatment and Diagnosis |
| title_fullStr | Food Allergies - Trends and Challenges in Treatment and Diagnosis |
| title_full_unstemmed | Food Allergies - Trends and Challenges in Treatment and Diagnosis |
| title_short | Food Allergies - Trends and Challenges in Treatment and Diagnosis |
| title_sort | food allergies trends and challenges in treatment and diagnosis |
| topic | food allergy Basophil Degranulation Test milk allergy peanut allergy |
| url | https://apcz.umk.pl/JEHS/article/view/45615 |
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