Very early remission and increased apoptosis with the use of Pentoxifylline in children with acute lymphoblastic leukemia

Very early remission and increased apoptosis with the use of Pentoxifylline in children with acute lymphoblastic leukemia

IntroductionDespite the improvement in survival in acute lymphoblastic leukemia (ALL), there are still cases with evasion of chemotherapy-induced apoptosis. The IKK/NF-κB signaling pathway contributes to antiapoptotic gene expression. Pentoxifylline (PTX) inhibits IkB phosphorylation, blocking NF-κB...

詳細記述

書誌詳細
主要な著者: Violeta Salceda-Rivera, Pablo C. Ortiz-Lazareno, Georgina Hernández-Flores, Jorge R. Vazquez-Urrutia, Jesus Meza-Arroyo, Monzerrat Pardo-Zepeda, Hugo Romo-Rubio, Cesar Barba-Barba, Fernando Sánchez-Zubieta, Carlos Alfredo Barrón-Gallardo, Oscar Gonzalez-Ramella, Alejandro Bravo-Cuellar
フォーマット: 論文
言語:English
出版事項: Frontiers Media S.A. 2024-10-01
シリーズ:Frontiers in Oncology
主題:
MRD
ALL
clinical trials
apoptosis
Pentoxifylline
early remission
オンライン･アクセス:https://www.frontiersin.org/articles/10.3389/fonc.2024.1401262/full

インターネット

https://www.frontiersin.org/articles/10.3389/fonc.2024.1401262/full

類似資料