A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in Dogs
The objective of this work was the comparative evaluation of the healing process after employing 4/0 poliglecaprone 25 and 4/0 polyglytone 6211 in a continuous intradermal suture pattern. Ten Beagle dogs were used, in which skin incisions were created surgically and subsequently were sutured by mean...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-10-01
|
| Series: | Animals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2615/11/11/3094 |
| _version_ | 1797410926569193472 |
|---|---|
| author | Pagona Gouletsou Nikitas Prassinos Lysimachos Papazoglou Polychronis Kostoulas Apostolos Galatos |
| author_facet | Pagona Gouletsou Nikitas Prassinos Lysimachos Papazoglou Polychronis Kostoulas Apostolos Galatos |
| author_sort | Pagona Gouletsou |
| collection | DOAJ |
| description | The objective of this work was the comparative evaluation of the healing process after employing 4/0 poliglecaprone 25 and 4/0 polyglytone 6211 in a continuous intradermal suture pattern. Ten Beagle dogs were used, in which skin incisions were created surgically and subsequently were sutured by means of continuous intradermal pattern using polyglytone 6211 or poliglecaprone 25 suture. Cosmetic, clinical, and histologic scores were evaluated. The cosmetic appearance of the wounds was blindly evaluated on days 7, 14, 28, 180, 360, 730, and 1095. On the same days, tissue biopsy was performed for histological evaluation. Clinical evaluation was performed initially daily, then weekly, monthly, and finally yearly, till day 1095. The clinical appearance of the intradermal pattern with both sutures was initially very good, deteriorated in the second post-operative month and thereafter improved. The cosmetic, clinical, and histological differences between the two suture materials were minimal and statistically insignificant. Polyglytone 6211 is sufficient for use in intradermal suturing in dogs. However, its earlier absorption compared to poliglecaprone 25 did not have any beneficial effect on cutaneous wound healing and scar appearance in the experimental animals. |
| first_indexed | 2024-03-09T04:37:30Z |
| format | Article |
| id | doaj.art-eaa809ca75434b0e890bd82c0c71b76a |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T04:37:30Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-eaa809ca75434b0e890bd82c0c71b76a2023-12-03T13:27:28ZengMDPI AGAnimals2076-26152021-10-011111309410.3390/ani11113094A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in DogsPagona Gouletsou0Nikitas Prassinos1Lysimachos Papazoglou2Polychronis Kostoulas3Apostolos Galatos4Clinic of Obstetrics and Reproduction, Faculty of Veterinary Science, School of Health Sciences, University of Thessaly, Trikalon 224, 43100 Karditsa, GreeceCompanion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, S Boutyra 11, 54627 Thessaloniki, GreeceCompanion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, S Boutyra 11, 54627 Thessaloniki, GreeceLaboratory of Epidemiology, Faculty of Public Health, School of Health Sciences, University of Thessaly, Terma Mavromichali, 43131 Karditsa, GreeceClinic of Surgery, Faculty of Veterinary Science, School of Health Sciences, University of Thessaly, Trikalon 224, 43100 Karditsa, GreeceThe objective of this work was the comparative evaluation of the healing process after employing 4/0 poliglecaprone 25 and 4/0 polyglytone 6211 in a continuous intradermal suture pattern. Ten Beagle dogs were used, in which skin incisions were created surgically and subsequently were sutured by means of continuous intradermal pattern using polyglytone 6211 or poliglecaprone 25 suture. Cosmetic, clinical, and histologic scores were evaluated. The cosmetic appearance of the wounds was blindly evaluated on days 7, 14, 28, 180, 360, 730, and 1095. On the same days, tissue biopsy was performed for histological evaluation. Clinical evaluation was performed initially daily, then weekly, monthly, and finally yearly, till day 1095. The clinical appearance of the intradermal pattern with both sutures was initially very good, deteriorated in the second post-operative month and thereafter improved. The cosmetic, clinical, and histological differences between the two suture materials were minimal and statistically insignificant. Polyglytone 6211 is sufficient for use in intradermal suturing in dogs. However, its earlier absorption compared to poliglecaprone 25 did not have any beneficial effect on cutaneous wound healing and scar appearance in the experimental animals.https://www.mdpi.com/2076-2615/11/11/3094caninepolyglytone 6211poliglecaprone 25intradermalwound healing |
| spellingShingle | Pagona Gouletsou Nikitas Prassinos Lysimachos Papazoglou Polychronis Kostoulas Apostolos Galatos A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in Dogs Animals canine polyglytone 6211 poliglecaprone 25 intradermal wound healing |
| title | A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in Dogs |
| title_full | A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in Dogs |
| title_fullStr | A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in Dogs |
| title_full_unstemmed | A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in Dogs |
| title_short | A Controlled Trial of Polyglytone 6211 versus Poliglecaprone 25 for Use in Intradermal Suturing in Dogs |
| title_sort | controlled trial of polyglytone 6211 versus poliglecaprone 25 for use in intradermal suturing in dogs |
| topic | canine polyglytone 6211 poliglecaprone 25 intradermal wound healing |
| url | https://www.mdpi.com/2076-2615/11/11/3094 |
| work_keys_str_mv | AT pagonagouletsou acontrolledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT nikitasprassinos acontrolledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT lysimachospapazoglou acontrolledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT polychroniskostoulas acontrolledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT apostolosgalatos acontrolledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT pagonagouletsou controlledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT nikitasprassinos controlledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT lysimachospapazoglou controlledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT polychroniskostoulas controlledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs AT apostolosgalatos controlledtrialofpolyglytone6211versuspoliglecaprone25foruseinintradermalsuturingindogs |