Profile of serum microRNAs in heart failure with reduced and preserved ejection fraction: Correlation with myocardial remodeling

Profile of serum microRNAs in heart failure with reduced and preserved ejection fraction: Correlation with myocardial remodeling

Background and aims: Cardiomyocyte hypertrophy and interstitial fibrosis are key components of myocardial remodeling in Heart Failure (HF) with preserved (HFpEF) or reduced ejection fraction (HFrEF). MicroRNAs (miRNAs) are non-coding, evolutionarily conserved RNA molecules that may offer novel insig...

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Bibliographic Details
Main Authors: Layde Rosane Paim, Luis Miguel da Silva, Lígia M. Antunes-Correa, Vinicius Citelli Ribeiro, Roberto Schreiber, Eduarda O.Z. Minin, Larissa C.M. Bueno, Elisangela C.P. Lopes, Renan Yamaguti, Andréa Coy-Canguçu, Sergio San Juan Dertkigil, Andrei Sposito, Jose Roberto Matos-Souza, Thiago Quinaglia, Tomas G. Neilan, Licio A. Velloso, Wilson Nadruz, Michael Jerosch-Herold, Otavio R. Coelho-Filho
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Heart failure
Biomarkers
MicroRNA
Interstitial fibrosis
Myocardial remodeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024032377

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