Effect of Saffron Extract, Astaxanthin, and Carnosic Acid on the Levels of Matrix Metalloproteinase-9 and on Body Weight Changes in Arthritis Experiments
The aim of this study was to explore the potential effect of natural compounds and their combination with methotrexate (M) on levels of matrix metalloproteinase-9 (MMP-9) as a key biochemical parameter in rat adjuvant arthritis. Further change of body weight was selected as one of clinical parameter...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2023-03-01
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| Series: | European Pharmaceutical Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/afpuc-2022-0016 |
| _version_ | 1797773511191691264 |
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| author | Chrastina M Póništ S Dráfi F Švík K Khademnematolahi S Pružinská K Tchorbanov A Bauerová K |
| author_facet | Chrastina M Póništ S Dráfi F Švík K Khademnematolahi S Pružinská K Tchorbanov A Bauerová K |
| author_sort | Chrastina M |
| collection | DOAJ |
| description | The aim of this study was to explore the potential effect of natural compounds and their combination with methotrexate (M) on levels of matrix metalloproteinase-9 (MMP-9) as a key biochemical parameter in rat adjuvant arthritis. Further change of body weight was selected as one of clinical parameters monitored in this animal model. |
| first_indexed | 2024-03-12T22:06:34Z |
| format | Article |
| id | doaj.art-eaae347b054c40f0bb5d5dcf42a36c83 |
| institution | Directory Open Access Journal |
| issn | 2453-6725 |
| language | English |
| last_indexed | 2024-03-12T22:06:34Z |
| publishDate | 2023-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | European Pharmaceutical Journal |
| spelling | doaj.art-eaae347b054c40f0bb5d5dcf42a36c832023-07-24T11:19:44ZengSciendoEuropean Pharmaceutical Journal2453-67252023-03-01692263310.2478/afpuc-2022-0016Effect of Saffron Extract, Astaxanthin, and Carnosic Acid on the Levels of Matrix Metalloproteinase-9 and on Body Weight Changes in Arthritis ExperimentsChrastina M0Póništ S1Dráfi F2Švík K3Khademnematolahi S4Pružinská K5Tchorbanov A6Bauerová K7Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, SlovakiaCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, SlovakiaCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, SlovakiaCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, SlovakiaCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, SlovakiaCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, SlovakiaThe Stephan Angeloff Institute of Microbiology (SAIM), Bulgarian Academy of Sciences, Sofia, BulgariaCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, SlovakiaThe aim of this study was to explore the potential effect of natural compounds and their combination with methotrexate (M) on levels of matrix metalloproteinase-9 (MMP-9) as a key biochemical parameter in rat adjuvant arthritis. Further change of body weight was selected as one of clinical parameters monitored in this animal model.https://doi.org/10.2478/afpuc-2022-0016astaxanthinsaffron extractcarnosic acidadjuvant arthritismmp-9 |
| spellingShingle | Chrastina M Póništ S Dráfi F Švík K Khademnematolahi S Pružinská K Tchorbanov A Bauerová K Effect of Saffron Extract, Astaxanthin, and Carnosic Acid on the Levels of Matrix Metalloproteinase-9 and on Body Weight Changes in Arthritis Experiments European Pharmaceutical Journal astaxanthin saffron extract carnosic acid adjuvant arthritis mmp-9 |
| title | Effect of Saffron Extract, Astaxanthin, and Carnosic Acid on the Levels of Matrix Metalloproteinase-9 and on Body Weight Changes in Arthritis Experiments |
| title_full | Effect of Saffron Extract, Astaxanthin, and Carnosic Acid on the Levels of Matrix Metalloproteinase-9 and on Body Weight Changes in Arthritis Experiments |
| title_fullStr | Effect of Saffron Extract, Astaxanthin, and Carnosic Acid on the Levels of Matrix Metalloproteinase-9 and on Body Weight Changes in Arthritis Experiments |
| title_full_unstemmed | Effect of Saffron Extract, Astaxanthin, and Carnosic Acid on the Levels of Matrix Metalloproteinase-9 and on Body Weight Changes in Arthritis Experiments |
| title_short | Effect of Saffron Extract, Astaxanthin, and Carnosic Acid on the Levels of Matrix Metalloproteinase-9 and on Body Weight Changes in Arthritis Experiments |
| title_sort | effect of saffron extract astaxanthin and carnosic acid on the levels of matrix metalloproteinase 9 and on body weight changes in arthritis experiments |
| topic | astaxanthin saffron extract carnosic acid adjuvant arthritis mmp-9 |
| url | https://doi.org/10.2478/afpuc-2022-0016 |
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