Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyladenosine Modification

Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyladenosine Modification

Activity-regulated cytoskeleton-associated protein (ARC) is activated by the induction of long-term potentiation and plays an important role in the synaptic plasticity of memory consolidation. Previous studies have shown that abnormal expression of ARC in the brains of patients with Alzheimer’s Dise...

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Bibliographic Details
Main Authors:	Chenhaoyi Xu, Huanghuang Huang, Min Zhang, Pei Zhang, Zezhi Li, Xueyuan Liu, Min Fang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-04-01
Series:	Frontiers in Aging Neuroscience
Subjects:	N6-methyladenosine (m6A) methyltransferase-like 3 (METTL3) YTH domain family member 1 (YTHDF1) activity-regulated cytoskeleton-associated protein (ARC) Alzheimer’s Disease (AD)
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2022.890134/full

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