Interferon-γ inhibits group B Streptococcus survival within human endothelial cells

Interferon-γ inhibits group B Streptococcus survival within human endothelial cells

Endothelial dysfunction is a major component of the pathophysiology of septicaemic group B Streptococcus (GBS) infections. Although cytokines have been shown to activate human umbilical vein endothelial cells (HUVECs), the capacity of interferon (IFN)-γ to enhance the microbicidal activity of HUVECs...

Full description

Bibliographic Details
Main Authors:	Viviane de Oliveira Freitas Lione, Michelle Hanthequeste Bittencourt dos Santos, Jessica Silva Santos de Oliveira, Ana Luiza Mattos-Guaraldi, Prescilla Emy Nagao
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2014-11-01
Series:	Memorias do Instituto Oswaldo Cruz
Subjects:	group B Streptococcus IFN-γ survival
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000700940&lng=en&tlng=en

Similar Items

Role of interferon-gamma (IFN-γ) and IFN-γ receptor 1/2 (IFNγR1/2) in regulation of immunity, infection, and cancer development: IFN-γ-dependent or independent pathway
by: Huihui Ding, et al.
Published: (2022-11-01)

Identification and characterization of interferon-γ signaling-based personalized heterogeneity and therapeutic strategies in patients with pancreatic cancer
by: Xu Chen, et al.
Published: (2023-10-01)

Interferons-α and -γ in clinical veterinary practice in the prevention and treatment of infectious diseases in cattle and pigs (review)
by: S. V. Shabunin, et al.
Published: (2022-02-01)

Forms and Methods for Interferon’s Encapsulation
by: Thelvia I. Ramos, et al.
Published: (2021-09-01)

Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes
by: Hankun Wang, et al.
Published: (2023-04-01)

Reactive oxygen species generation mediated by NADPH oxidase and PI3K/Akt pathways contribute to invasion of Streptococcus agalactiae in human endothelial cells
by: Jessica Silva Santos de Oliveira, et al.
Published: (2018-04-01)

Comparative analysis of intradermal tuberculin test and γ-interferon assay for diagnosis of bovine tuberculosis
by: S S VYAVAHARE, et al.
Published: (2022-09-01)

Role of Interferons in <em>Mycobacterium tuberculosis</em> Infection
by: Gaithrri Shanmuganathan, et al.
Published: (2022-09-01)

Insertion of an immunodominant T helper cell epitope within the Group A Streptococcus M protein promotes an IFN-γ-dependent shift from a non-protective to a protective immune response
by: Shiva Emami, et al.
Published: (2023-08-01)

Salivary interleukin-17A and interferon-γ levels are elevated in children with food allergies in China
by: Yan Yin, et al.
Published: (2023-11-01)

Galectin-9 and Interferon-Gamma Are Released by Natural Killer Cells upon Activation with Interferon-Alpha and Orchestrate the Suppression of Hepatitis C Virus Infection
by: Anna Paola Carreca, et al.
Published: (2022-07-01)

Immunomodulatory Role of Interferons in Viral and Bacterial Infections
by: Paulina Mertowska, et al.
Published: (2023-06-01)

Interferon-γ Preferentially Promotes Necroptosis of Lung Epithelial Cells by Upregulating MLKL
by: Qin Hao, et al.
Published: (2022-02-01)

Inflammatory activation of the FcγR and IFNγR pathways co-influences the differentiation and activity of osteoclasts
by: Bettina Groetsch, et al.
Published: (2022-09-01)

Type 1–type 2 interferon imbalance in dry eye disease
by: Trailokyanath Panigrahi, et al.
Published: (2023-01-01)

The host transcriptome change involved in the inhibitory effect of exogenous interferon-γ on Getah virus replication
by: Jialei Li, et al.
Published: (2023-06-01)

Pin-Pointing the Key Hubs in the IFN-γ Pathway Responding to SARS-CoV-2 Infection
by: Ayelen Toro, et al.
Published: (2022-09-01)

The Profile of Interferon-ɣ and BCG Scar as an Immune Response Reflection in Children with Leprosy
by: Renata Mayangsari, et al.
Published: (2017-01-01)

Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids
by: Michael J. Workman, et al.
Published: (2020-12-01)

Small Molecule Inhibitors Targeting Nuclear Factor κB Activation Markedly Reduce Expression of Interleukin-2, but Not Interferon-γ, Induced by Phorbol Esters and Calcium Ionophores
by: Yumiko Tanaka, et al.
Published: (2021-12-01)

Parkin Promotes Airway Inflammatory Response to Interferon Gamma
by: Kris Genelyn Dimasuay, et al.
Published: (2023-10-01)

The Role of Interleukine-10 and Interferon-γ as Potential Markers of the Evolution of African Swine Fever Virus Infection in Wild Boar
by: Sandra Barroso-Arévalo, et al.
Published: (2021-06-01)

Hemoparasites effect on interferon-gamma and miRNA 125b expression in Bubalus bubalis
by: Cintia L. Santos, et al.
Published: (2024-01-01)

Low doses of IgG from atopic individuals can modulate in vitro IFN-γ production by human intra-thymic TCD4 and TCD8 cells: An IVIg comparative approach
by: Fábio da Ressureição Sgnotto, et al.
Published: (2017-07-01)

Prediction of Conserved Peptides of <i>Paracoccidioides</i> for Interferon-γ Release Assay: The First Step in the Development of a Lab-Based Approach for Immunological Assessment during Antifungal Therapy
by: Sarah Brena Aparecida Rosa, et al.
Published: (2020-12-01)

Antibody-dependent enhancement of porcine reproductive and respiratory syndrome virus infection downregulates the levels of interferon-gamma/lambdas in porcine alveolar macrophages in vitro
by: Liujun Zhang, et al.
Published: (2023-03-01)

Nasopharyngeal and Peripheral Blood Type II Interferon Signature Evaluation in Infants during Respiratory Syncytial Virus Infection
by: Francesco Savino, et al.
Published: (2024-02-01)

Toxoplasma IWS1 Determines Fitness in Interferon-γ-Activated Host Cells and Mice by Indirectly Regulating ROP18 mRNA Expression
by: Emi Hashizaki, et al.
Published: (2023-02-01)

Single nucleotide polymorphisms in the interferon gamma gene are associated with distinct types of retinochoroidal scar lesions presumably caused by Toxoplasma gondii infection
by: Ricardo Guerra Peixe, et al.
Published: (2014-02-01)

Interferon and interferon-stimulated genes in HBV treatment
by: Qirong Li, et al.
Published: (2022-12-01)

Disturbed natural killer cell homeostasis in the salivary gland enhances autoimmune pathology via IFN-γ in a mouse model of primary Sjögren’s syndrome
by: Mami Sato, et al.
Published: (2022-10-01)

Association of Interferon-gamma Gene Polymorphism (+874 A/T) and Oral Lichen planus susceptibility: Systematic Review and Meta-Analysis
by: paria motahari, et al.
Published: (2019-09-01)

Hormone therapy affecting interferon defense in children with infectious mononucleosis
by: I. M. Fedorova, et al.
Published: (2021-11-01)

Mycobacterial Hsp65 antigen upregulates the cellular immune response of healthy individuals compared with tuberculosis patients
by: Pryscilla Fanini Wowk, et al.
Published: (2017-05-01)

Fabrication of an Electrochemical Aptasensor Composed of Multifunctional DNA Three-Way Junction on Au Microgap Electrode for Interferon Gamma Detection in Human Serum
by: Seungwoo Noh, et al.
Published: (2021-06-01)

IFNγ-Producing B Cells Play a Regulating Role in Infection-Mediated Inhibition of Allergy
by: Sai Qiao, et al.
Published: (2023-09-01)

The Crosstalk between the EGFR and IFN-γ Pathways and Synergistic Roles in Survival Prediction and Immune Escape in Gliomas
by: Xingang Zhou, et al.
Published: (2023-09-01)

The Impact of IL-18 and IFN-γ on Severity of Malaria and Quality of Treatment
by: Gholam-Reza Ameri, et al.
Published: (2014-11-01)

PD-1+ IFN-γ+ subset of CD8+ T cell in circulation predicts response to anti–PD-1 therapy in NSCLC
by: Wenxiu Chen, et al.
Published: (2023-06-01)

Interferon gamma effect on immune mediator production in human nerve cells infected by two strains of Toxoplasma gondii
by: Mammari Nour, et al.
Published: (2015-01-01)