The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse.

The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse.

Adhesion-GPCRs provide essential cell-cell and cell-matrix interactions in development, and have been implicated in inherited human diseases like Usher Syndrome and bilateral frontoparietal polymicrogyria. They are the second largest subfamily of seven-transmembrane spanning proteins in vertebrates,...

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Bibliographic Details
Main Authors:	Helen Waller-Evans, Simone Prömel, Tobias Langenhan, John Dixon, Dirk Zahn, William H Colledge, Joanne Doran, Mark B L Carlton, Ben Davies, Samuel A J R Aparicio, Johannes Grosse, Andreas P Russ
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-11-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2987804?pdf=render

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