Progress of angiotensin converting enzyme 2 in cardiovascular diseases

Angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV and SARS-CoV-2(severe acute respiratory syndrom coronavirus 2) viruses, and it is also one of the main family members of renin-angiotensin-aldosterone system. ACE2 has a protective effect on cardiovascular diseases and inhibits the...

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Main Author: JIAO Xiao-lu, QIN Yan-wen
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2020-05-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200269.pdf
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author JIAO Xiao-lu, QIN Yan-wen
author_facet JIAO Xiao-lu, QIN Yan-wen
author_sort JIAO Xiao-lu, QIN Yan-wen
collection DOAJ
description Angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV and SARS-CoV-2(severe acute respiratory syndrom coronavirus 2) viruses, and it is also one of the main family members of renin-angiotensin-aldosterone system. ACE2 has a protective effect on cardiovascular diseases and inhibits the development of cardiovascular diseases. SARS-CoV-2 reduces the expression of ACE2 of host, which may be one of the reasons for cardiovascular complications in the later stage of coronavirus disease 2019(COVID-19). Thus, the role and mechanism of ACE2 in the development of cardiovascular diseases were summarized in this article in order to provide potential stratigy development for the treatment of COVID-19.
first_indexed 2024-03-08T16:53:27Z
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issn 1001-6325
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last_indexed 2024-03-08T16:53:27Z
publishDate 2020-05-01
publisher Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
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series Jichu yixue yu linchuang
spelling doaj.art-eab20da853d64822a7655c2f20950c6d2024-01-05T03:15:38ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252020-05-01405701706Progress of angiotensin converting enzyme 2 in cardiovascular diseasesJIAO Xiao-lu, QIN Yan-wen0the Key Laboratory of Upper Airway Dysfunction-related Cardiovascular Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, ChinaAngiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV and SARS-CoV-2(severe acute respiratory syndrom coronavirus 2) viruses, and it is also one of the main family members of renin-angiotensin-aldosterone system. ACE2 has a protective effect on cardiovascular diseases and inhibits the development of cardiovascular diseases. SARS-CoV-2 reduces the expression of ACE2 of host, which may be one of the reasons for cardiovascular complications in the later stage of coronavirus disease 2019(COVID-19). Thus, the role and mechanism of ACE2 in the development of cardiovascular diseases were summarized in this article in order to provide potential stratigy development for the treatment of COVID-19.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200269.pdfangiotensin-converting enzyme 2|cardiovascular diseases|renin-angiotensin-aldosterone system
spellingShingle JIAO Xiao-lu, QIN Yan-wen
Progress of angiotensin converting enzyme 2 in cardiovascular diseases
Jichu yixue yu linchuang
angiotensin-converting enzyme 2|cardiovascular diseases|renin-angiotensin-aldosterone system
title Progress of angiotensin converting enzyme 2 in cardiovascular diseases
title_full Progress of angiotensin converting enzyme 2 in cardiovascular diseases
title_fullStr Progress of angiotensin converting enzyme 2 in cardiovascular diseases
title_full_unstemmed Progress of angiotensin converting enzyme 2 in cardiovascular diseases
title_short Progress of angiotensin converting enzyme 2 in cardiovascular diseases
title_sort progress of angiotensin converting enzyme 2 in cardiovascular diseases
topic angiotensin-converting enzyme 2|cardiovascular diseases|renin-angiotensin-aldosterone system
url http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200269.pdf
work_keys_str_mv AT jiaoxiaoluqinyanwen progressofangiotensinconvertingenzyme2incardiovasculardiseases