Progress of angiotensin converting enzyme 2 in cardiovascular diseases
Angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV and SARS-CoV-2(severe acute respiratory syndrom coronavirus 2) viruses, and it is also one of the main family members of renin-angiotensin-aldosterone system. ACE2 has a protective effect on cardiovascular diseases and inhibits the...
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Format: | Article |
Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2020-05-01
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Series: | Jichu yixue yu linchuang |
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Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200269.pdf |
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author | JIAO Xiao-lu, QIN Yan-wen |
author_facet | JIAO Xiao-lu, QIN Yan-wen |
author_sort | JIAO Xiao-lu, QIN Yan-wen |
collection | DOAJ |
description | Angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV and SARS-CoV-2(severe acute respiratory syndrom coronavirus 2) viruses, and it is also one of the main family members of renin-angiotensin-aldosterone system. ACE2 has a protective effect on cardiovascular diseases and inhibits the development of cardiovascular diseases. SARS-CoV-2 reduces the expression of ACE2 of host, which may be one of the reasons for cardiovascular complications in the later stage of coronavirus disease 2019(COVID-19). Thus, the role and mechanism of ACE2 in the development of cardiovascular diseases were summarized in this article in order to provide potential stratigy development for the treatment of COVID-19. |
first_indexed | 2024-03-08T16:53:27Z |
format | Article |
id | doaj.art-eab20da853d64822a7655c2f20950c6d |
institution | Directory Open Access Journal |
issn | 1001-6325 |
language | zho |
last_indexed | 2024-03-08T16:53:27Z |
publishDate | 2020-05-01 |
publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
record_format | Article |
series | Jichu yixue yu linchuang |
spelling | doaj.art-eab20da853d64822a7655c2f20950c6d2024-01-05T03:15:38ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252020-05-01405701706Progress of angiotensin converting enzyme 2 in cardiovascular diseasesJIAO Xiao-lu, QIN Yan-wen0the Key Laboratory of Upper Airway Dysfunction-related Cardiovascular Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing 100029, ChinaAngiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV and SARS-CoV-2(severe acute respiratory syndrom coronavirus 2) viruses, and it is also one of the main family members of renin-angiotensin-aldosterone system. ACE2 has a protective effect on cardiovascular diseases and inhibits the development of cardiovascular diseases. SARS-CoV-2 reduces the expression of ACE2 of host, which may be one of the reasons for cardiovascular complications in the later stage of coronavirus disease 2019(COVID-19). Thus, the role and mechanism of ACE2 in the development of cardiovascular diseases were summarized in this article in order to provide potential stratigy development for the treatment of COVID-19.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200269.pdfangiotensin-converting enzyme 2|cardiovascular diseases|renin-angiotensin-aldosterone system |
spellingShingle | JIAO Xiao-lu, QIN Yan-wen Progress of angiotensin converting enzyme 2 in cardiovascular diseases Jichu yixue yu linchuang angiotensin-converting enzyme 2|cardiovascular diseases|renin-angiotensin-aldosterone system |
title | Progress of angiotensin converting enzyme 2 in cardiovascular diseases |
title_full | Progress of angiotensin converting enzyme 2 in cardiovascular diseases |
title_fullStr | Progress of angiotensin converting enzyme 2 in cardiovascular diseases |
title_full_unstemmed | Progress of angiotensin converting enzyme 2 in cardiovascular diseases |
title_short | Progress of angiotensin converting enzyme 2 in cardiovascular diseases |
title_sort | progress of angiotensin converting enzyme 2 in cardiovascular diseases |
topic | angiotensin-converting enzyme 2|cardiovascular diseases|renin-angiotensin-aldosterone system |
url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200269.pdf |
work_keys_str_mv | AT jiaoxiaoluqinyanwen progressofangiotensinconvertingenzyme2incardiovasculardiseases |