BMP4 is a peripherally-derived factor for motor neurons and attenuates glutamate-induced excitotoxicity in vitro.
Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGF-β) superfamily, have been shown to play important roles in the nervous system, including neuronal survival and synaptogenesis. However, the physiological functions of BMP signaling in the mammalian neuromuscular...
Main Authors: | Hui-Ju Chou, Dar-Ming Lai, Cheng-Wen Huang, Ian S McLennan, Horng-Dar Wang, Pei-Yu Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3589418?pdf=render |
Similar Items
-
THE ROLE OF GLUTAMATE METABOLISM IN NEURONAL EXCITOTOXICITY
by: Vanessa Göschl, et al.
Published: (2023-10-01) -
Isoliquiritigenin Protects Neuronal Cells against Glutamate Excitotoxicity
by: Arina Zgodova, et al.
Published: (2022-10-01) -
Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity
by: Irina Krasil’nikova, et al.
Published: (2019-09-01) -
NSC-34 motor neuron-like cells are unsuitable as experimental model for glutamate-mediated excitotoxicity
by: Blandine eMadji Hounoum, et al.
Published: (2016-05-01) -
Glutamate excitotoxicity in multiple sclerosis
by: A. A. Ryazantseva, et al.
Published: (2017-02-01)