Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive Review

Kudzu root (Pueraria lobate (Willd.) Ohwi, KR) is an edible plant with rich nutritional and medicinal values. Over the past few decades, an ample variety of biological effects of Pueraria isoflavone have been evaluated. Evidence has shown that Pueraria isoflavone can play an active role in antioxida...

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Main Authors: Tong Xuan, Yuhan Liu, Rui Liu, Sheng Liu, Jiaqi Han, Xinyu Bai, Jie Wu, Ronghua Fan
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/18/6577
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author Tong Xuan
Yuhan Liu
Rui Liu
Sheng Liu
Jiaqi Han
Xinyu Bai
Jie Wu
Ronghua Fan
author_facet Tong Xuan
Yuhan Liu
Rui Liu
Sheng Liu
Jiaqi Han
Xinyu Bai
Jie Wu
Ronghua Fan
author_sort Tong Xuan
collection DOAJ
description Kudzu root (Pueraria lobate (Willd.) Ohwi, KR) is an edible plant with rich nutritional and medicinal values. Over the past few decades, an ample variety of biological effects of Pueraria isoflavone have been evaluated. Evidence has shown that Pueraria isoflavone can play an active role in antioxidant, anti-inflammatory, anti-cancer, neuroprotection, and cardiovascular protection. Over 50 isoflavones in kudzu root have been identified, including puerarin, daidzein, daidzin, 3′-hydroxy puerarin, and genistein, each with unambiguous structures. However, the application of these isoflavones in the development of functional food and health food still depends on the extraction, purification and identification technology of Pueraria isoflavone. In recent years, many green and novel extraction, purification, and identification techniques have been developed for the preparation of Pueraria isoflavone. This review provides an updated overview of these techniques, specifically for isoflavones in KR since 2018, and also discusses and compares the advantages and disadvantages of these techniques in depth. The intention is to provide a research basis for the green and efficient extraction, purification, and identification of Pueraria isoflavone and offers investigators a valuable reference for future studies on the KR.
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spelling doaj.art-eab45202dc8244cf9b6905cdb8f0a1e62023-11-19T12:09:24ZengMDPI AGMolecules1420-30492023-09-012818657710.3390/molecules28186577Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive ReviewTong Xuan0Yuhan Liu1Rui Liu2Sheng Liu3Jiaqi Han4Xinyu Bai5Jie Wu6Ronghua Fan7Department of Sanitary Inspection, School of Public Health, Shenyang Medical College, Shenyang 110034, ChinaDepartment of Sanitary Inspection, School of Public Health, Shenyang Medical College, Shenyang 110034, ChinaDepartment of Sanitary Inspection, School of Public Health, Shenyang Medical College, Shenyang 110034, ChinaDepartment of Sanitary Inspection, School of Public Health, Shenyang Medical College, Shenyang 110034, ChinaDepartment of Sanitary Inspection, School of Public Health, Shenyang Medical College, Shenyang 110034, ChinaDepartment of Sanitary Inspection, School of Public Health, Shenyang Medical College, Shenyang 110034, ChinaDepartment of Sanitary Inspection, School of Public Health, Shenyang Medical College, Shenyang 110034, ChinaDepartment of Sanitary Inspection, School of Public Health, Shenyang Medical College, Shenyang 110034, ChinaKudzu root (Pueraria lobate (Willd.) Ohwi, KR) is an edible plant with rich nutritional and medicinal values. Over the past few decades, an ample variety of biological effects of Pueraria isoflavone have been evaluated. Evidence has shown that Pueraria isoflavone can play an active role in antioxidant, anti-inflammatory, anti-cancer, neuroprotection, and cardiovascular protection. Over 50 isoflavones in kudzu root have been identified, including puerarin, daidzein, daidzin, 3′-hydroxy puerarin, and genistein, each with unambiguous structures. However, the application of these isoflavones in the development of functional food and health food still depends on the extraction, purification and identification technology of Pueraria isoflavone. In recent years, many green and novel extraction, purification, and identification techniques have been developed for the preparation of Pueraria isoflavone. This review provides an updated overview of these techniques, specifically for isoflavones in KR since 2018, and also discusses and compares the advantages and disadvantages of these techniques in depth. The intention is to provide a research basis for the green and efficient extraction, purification, and identification of Pueraria isoflavone and offers investigators a valuable reference for future studies on the KR.https://www.mdpi.com/1420-3049/28/18/6577puerarin isoflavoneextractionpurificationanalysis techniques
spellingShingle Tong Xuan
Yuhan Liu
Rui Liu
Sheng Liu
Jiaqi Han
Xinyu Bai
Jie Wu
Ronghua Fan
Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive Review
Molecules
puerarin isoflavone
extraction
purification
analysis techniques
title Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive Review
title_full Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive Review
title_fullStr Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive Review
title_full_unstemmed Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive Review
title_short Advances in Extraction, Purification, and Analysis Techniques of the Main Components of Kudzu Root: A Comprehensive Review
title_sort advances in extraction purification and analysis techniques of the main components of kudzu root a comprehensive review
topic puerarin isoflavone
extraction
purification
analysis techniques
url https://www.mdpi.com/1420-3049/28/18/6577
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