An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification

An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification

Abstract Background Compound Kushen Injection (CKI) is a Chinese patent drug that exerts curative effects in the clinical treatment of hepatocellular carcinoma (HCC). This study aimed to explore the targets and potential pharmacological mechanisms of CKI in the treatment of HCC. Methods In this stud...

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Bibliographic Details
Main Authors: Shan Lu, Ziqi Meng, Yingying Tan, Chao Wu, Zhihong Huang, Jiaqi Huang, Changgeng Fu, Antony Stalin, Siyu Guo, Xinkui Liu, Leiming You, Xiaojiaoyang Li, Jingyuan Zhang, Wei Zhou, Xiaomeng Zhang, Miaomiao Wang, Jiarui Wu
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Compound Kushen Injection
Hepatocellular carcinoma
Network pharmacology
Proliferation
Online Access:https://doi.org/10.1186/s12906-022-03530-3

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