Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells.

Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells.

<h4>Background & aims</h4>Hepatocyte-like cells (HLCs) differentiated from induced pluripotent stem cells (iPSCs) have emerged as a promising cell culture model to study metabolism, biotransformation, viral infections and inherited liver diseases. iPSCs provide an unlimited supply fo...

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Main Authors: Diego Calabrese, Guglielmo Roma, Sebastian Bergling, Walter Carbone, Valentina Mele, Sandro Nuciforo, Isabel Fofana, Benedetta Campana, Dagmara Szkolnicka, David C Hay, Jan Tchorz, Tewis Bouwmeester, Stefan Wieland, Markus H Heim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221762

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