Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature review

Summary: In recent years, fetal or autologous stem cell transplant for the treatment of Parkinson's disease (PD) has been practiced in a few medical organizations. However, the potential complications related to the growth of allograft tissue have not yet been well described apart from case rep...

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Автори: Jaffar A. Al-Tawfiq, Ramzi W. Banda, Jihad Ghandour
Формат: Стаття
Мова:English
Опубліковано: Elsevier 2015-07-01
Серія:Journal of Infection and Public Health
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S1876034115000040
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author Jaffar A. Al-Tawfiq
Ramzi W. Banda
Jihad Ghandour
author_facet Jaffar A. Al-Tawfiq
Ramzi W. Banda
Jihad Ghandour
author_sort Jaffar A. Al-Tawfiq
collection DOAJ
description Summary: In recent years, fetal or autologous stem cell transplant for the treatment of Parkinson's disease (PD) has been practiced in a few medical organizations. However, the potential complications related to the growth of allograft tissue have not yet been well described apart from case reports. Here, we present a 42-year-old Saudi male who suffered from early onset Parkinson's disease. He sought medical care in China and received autologous intrathecal stem cell transplantation. He did not demonstrate any significant improvement. A few months later, the patient went back to China and underwent fetal cell transplantation into the left hemisphere and a second stem cell transplantation intrathecally. He presented with seizures and had a left frontal brain cyst. The cyst was drained and contained clear fluid. All cultures were negative. He had an uneventful recovery. Keywords: Brain abscess, Parkinsonism, Transplant, Brain cyst, Fetal stem cell
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spelling doaj.art-eab7abdac5d04d9baa8b2feb6567cde12022-12-21T18:04:52ZengElsevierJournal of Infection and Public Health1876-03412015-07-0184382385Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature reviewJaffar A. Al-Tawfiq0Ramzi W. Banda1Jihad Ghandour2Corresponding author at: Dhahran Health Center, Johns Hopkins Aramco Healthcare, Room A-428-2, Building 61, P.O. Box 76, Dhahran 31311, Saudi Arabia. Tel.: +966 13 877 9748; fax: +966 13 877 3790.; Specialty Internal Medicine Unit, Johns Hopkins Aramco Healthcare, Dhahran, Saudi ArabiaSpecialty Internal Medicine Unit, Johns Hopkins Aramco Healthcare, Dhahran, Saudi ArabiaSpecialty Internal Medicine Unit, Johns Hopkins Aramco Healthcare, Dhahran, Saudi ArabiaSummary: In recent years, fetal or autologous stem cell transplant for the treatment of Parkinson's disease (PD) has been practiced in a few medical organizations. However, the potential complications related to the growth of allograft tissue have not yet been well described apart from case reports. Here, we present a 42-year-old Saudi male who suffered from early onset Parkinson's disease. He sought medical care in China and received autologous intrathecal stem cell transplantation. He did not demonstrate any significant improvement. A few months later, the patient went back to China and underwent fetal cell transplantation into the left hemisphere and a second stem cell transplantation intrathecally. He presented with seizures and had a left frontal brain cyst. The cyst was drained and contained clear fluid. All cultures were negative. He had an uneventful recovery. Keywords: Brain abscess, Parkinsonism, Transplant, Brain cyst, Fetal stem cellhttp://www.sciencedirect.com/science/article/pii/S1876034115000040
spellingShingle Jaffar A. Al-Tawfiq
Ramzi W. Banda
Jihad Ghandour
Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature review
Journal of Infection and Public Health
title Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature review
title_full Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature review
title_fullStr Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature review
title_full_unstemmed Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature review
title_short Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature review
title_sort sterile cyst formation after intrathecal stem cell transplant for parkinson s disease a case presentation and literature review
url http://www.sciencedirect.com/science/article/pii/S1876034115000040
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AT jihadghandour sterilecystformationafterintrathecalstemcelltransplantforparkinsonsdiseaseacasepresentationandliteraturereview