Semen parameters in male carriers of Robertsonian translocations (13;14)
Background. Robertsonian translocations (RTs) are the most common type of balanced chromosomal abnormalities. RT male carriers have an increased risk of reproductive disorders, but the causes of this still are not clear enough.Aim. To evaluate semen parameters in RT(13;14) male carriers.Materials an...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2023-01-01
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| Series: | Андрология и генитальная хирургия |
| Subjects: | |
| Online Access: | https://agx.abvpress.ru/jour/article/view/619 |
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| author | M. V. Andreeva L. F. Kurilo M. I. Shtaut A. O. Sedova T. M. Sorokina V. B. Chernykh |
| author_facet | M. V. Andreeva L. F. Kurilo M. I. Shtaut A. O. Sedova T. M. Sorokina V. B. Chernykh |
| author_sort | M. V. Andreeva |
| collection | DOAJ |
| description | Background. Robertsonian translocations (RTs) are the most common type of balanced chromosomal abnormalities. RT male carriers have an increased risk of reproductive disorders, but the causes of this still are not clear enough.Aim. To evaluate semen parameters in RT(13;14) male carriers.Materials and methods. 24 men with 45,XY,der(13;14)(q10;q10) karyotype and infertility (n = 23) or recurrent pregnancy loss in spouse (n = 1).Results. Oligoasthenoteratozoospermia was detected in 18 (75 %) patients, asthenoteratozoospermia in 3 (13 %) patients, and azoospermia in 2 (8 %) patients. Normozoospermia was detected in 1 (4 %) patient, whose wife had a history of recurrent pregnancy loss.Conclusion. Infertility in the examined RT male carriers is associated with spermatogenesis disorders, in most cases resulted in oligozooasthenoteratozoospermia. |
| first_indexed | 2024-04-10T03:52:03Z |
| format | Article |
| id | doaj.art-eabc1fe6a167471393b7e538bde128c0 |
| institution | Directory Open Access Journal |
| issn | 2070-9781 |
| language | Russian |
| last_indexed | 2024-04-10T03:52:03Z |
| publishDate | 2023-01-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Андрология и генитальная хирургия |
| spelling | doaj.art-eabc1fe6a167471393b7e538bde128c02023-03-13T07:15:11ZrusABV-pressАндрология и генитальная хирургия2070-97812023-01-01234818910.17650/2070-9781-2022-23-4-81-89488Semen parameters in male carriers of Robertsonian translocations (13;14)M. V. Andreeva0L. F. Kurilo1M. I. Shtaut2A. O. Sedova3T. M. Sorokina4V. B. Chernykh5N.P. Bochkov Research Centre for Medical GeneticsN.P. Bochkov Research Centre for Medical GeneticsN.P. Bochkov Research Centre for Medical GeneticsN.P. Bochkov Research Centre for Medical GeneticsN.P. Bochkov Research Centre for Medical GeneticsN.P. Bochkov Research Centre for Medical GeneticsBackground. Robertsonian translocations (RTs) are the most common type of balanced chromosomal abnormalities. RT male carriers have an increased risk of reproductive disorders, but the causes of this still are not clear enough.Aim. To evaluate semen parameters in RT(13;14) male carriers.Materials and methods. 24 men with 45,XY,der(13;14)(q10;q10) karyotype and infertility (n = 23) or recurrent pregnancy loss in spouse (n = 1).Results. Oligoasthenoteratozoospermia was detected in 18 (75 %) patients, asthenoteratozoospermia in 3 (13 %) patients, and azoospermia in 2 (8 %) patients. Normozoospermia was detected in 1 (4 %) patient, whose wife had a history of recurrent pregnancy loss.Conclusion. Infertility in the examined RT male carriers is associated with spermatogenesis disorders, in most cases resulted in oligozooasthenoteratozoospermia.https://agx.abvpress.ru/jour/article/view/619robertsonian translocationsmale infertilitykaryotypespermsemen analysisoligozoospermiaazoospermia |
| spellingShingle | M. V. Andreeva L. F. Kurilo M. I. Shtaut A. O. Sedova T. M. Sorokina V. B. Chernykh Semen parameters in male carriers of Robertsonian translocations (13;14) Андрология и генитальная хирургия robertsonian translocations male infertility karyotype sperm semen analysis oligozoospermia azoospermia |
| title | Semen parameters in male carriers of Robertsonian translocations (13;14) |
| title_full | Semen parameters in male carriers of Robertsonian translocations (13;14) |
| title_fullStr | Semen parameters in male carriers of Robertsonian translocations (13;14) |
| title_full_unstemmed | Semen parameters in male carriers of Robertsonian translocations (13;14) |
| title_short | Semen parameters in male carriers of Robertsonian translocations (13;14) |
| title_sort | semen parameters in male carriers of robertsonian translocations 13 14 |
| topic | robertsonian translocations male infertility karyotype sperm semen analysis oligozoospermia azoospermia |
| url | https://agx.abvpress.ru/jour/article/view/619 |
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