Wnt Modulation Enhances Otic Differentiation by Facilitating the Enucleation Process but Develops Unnecessary Cardiac Structures

Wnt Modulation Enhances Otic Differentiation by Facilitating the Enucleation Process but Develops Unnecessary Cardiac Structures

Otic organoids have the potential to resolve current challenges in hearing loss research. The reproduction of the delicate and complex structure of the mammalian cochlea using organoids requires high efficiency and specificity. Recent attempts to strengthen otic organoids have focused on the effects...

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Bibliographic Details
Main Authors: Nathaniel T. Carpena, So-Young Chang, Ji-Eun Choi, Jae Yun Jung, Min Young Lee
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
otic organoid
wnt pathway
cardiac differentiation
Online Access:https://www.mdpi.com/1422-0067/22/19/10306

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