COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolytics
Coronavirus disease 2019 (COVID-19) is a global pandemic the world is dealing with currently. Clinical evidences suggest that the patients are predisposed to both venous and arterial thrombotic complications. This is because of severe inflammatory responses, injury to endothelium and activation of p...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2021;volume=10;issue=10;spage=3561;epage=3567;aulast=Khandelwal |
| _version_ | 1818402882016247808 |
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| author | Gaurav Khandelwal Avik Ray Samdish Sethi H K Harikrishnan Chaitanya Khandelwal Balakrishnan Sadasivam |
| author_facet | Gaurav Khandelwal Avik Ray Samdish Sethi H K Harikrishnan Chaitanya Khandelwal Balakrishnan Sadasivam |
| author_sort | Gaurav Khandelwal |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19) is a global pandemic the world is dealing with currently. Clinical evidences suggest that the patients are predisposed to both venous and arterial thrombotic complications. This is because of severe inflammatory responses, injury to endothelium and activation of platelets leading to increased coagulation. Additionally, individuals who are already receiving antithrombotic drug therapy for various cardiovascular diseases and complications might contract the disease in which case, attention should be given to the choice and duration of the therapy besides close monitoring of biochemical blood parameters. Herein, we review the incidences of thrombotic complications and their outcomes in COVID-19 patients as reported till date, while understanding the prophylactic and therapeutic roles of anticoagulants, antiplatelets and thrombolytics in the management of this severe viral respiratory illness. |
| first_indexed | 2024-12-14T08:15:25Z |
| format | Article |
| id | doaj.art-eac34ede0e354e8bb81a0d0174426d95 |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-12-14T08:15:25Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-eac34ede0e354e8bb81a0d0174426d952022-12-21T23:09:56ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632021-01-0110103561356710.4103/jfmpc.jfmpc_1297_20COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolyticsGaurav KhandelwalAvik RaySamdish SethiH K HarikrishnanChaitanya KhandelwalBalakrishnan SadasivamCoronavirus disease 2019 (COVID-19) is a global pandemic the world is dealing with currently. Clinical evidences suggest that the patients are predisposed to both venous and arterial thrombotic complications. This is because of severe inflammatory responses, injury to endothelium and activation of platelets leading to increased coagulation. Additionally, individuals who are already receiving antithrombotic drug therapy for various cardiovascular diseases and complications might contract the disease in which case, attention should be given to the choice and duration of the therapy besides close monitoring of biochemical blood parameters. Herein, we review the incidences of thrombotic complications and their outcomes in COVID-19 patients as reported till date, while understanding the prophylactic and therapeutic roles of anticoagulants, antiplatelets and thrombolytics in the management of this severe viral respiratory illness.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2021;volume=10;issue=10;spage=3561;epage=3567;aulast=Khandelwalanticoagulantantiplateletcoronavirus disease 2019sars-cov-2thrombolyticsthrombosis |
| spellingShingle | Gaurav Khandelwal Avik Ray Samdish Sethi H K Harikrishnan Chaitanya Khandelwal Balakrishnan Sadasivam COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolytics Journal of Family Medicine and Primary Care anticoagulant antiplatelet coronavirus disease 2019 sars-cov-2 thrombolytics thrombosis |
| title | COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolytics |
| title_full | COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolytics |
| title_fullStr | COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolytics |
| title_full_unstemmed | COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolytics |
| title_short | COVID-19 and thrombotic complications—the role of anticoagulants, antiplatelets and thrombolytics |
| title_sort | covid 19 and thrombotic complications the role of anticoagulants antiplatelets and thrombolytics |
| topic | anticoagulant antiplatelet coronavirus disease 2019 sars-cov-2 thrombolytics thrombosis |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2021;volume=10;issue=10;spage=3561;epage=3567;aulast=Khandelwal |
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