Reversibility of cardiac fibrosis in mice chronically infected with Trypanosoma cruzi, under specific chemotherapy

Reversibility of cardiac fibrosis in mice chronically infected with Trypanosoma cruzi, under specific chemotherapy

This investigation was performed to verify the effect of specific chemotherapy (Benznidazole or MK-346) on the inflammatory and fibrotic cardiac alterations in mice chronically infected with the strains 21 SF (Type II) and Colombian (Type III) of Trypanosoma cruzi. To obtain chronically infected mic...

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Bibliographic Details
Main Authors: Sonia G. Andrade, Sylviane Stocker-Guerret, Ariane S. Pimentel, Jean Alexis Grimaud
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1991-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Trypanosoma cruzi
chronic myocarditis
collagen immunotyping
fibronectin
laminin
chemotherapy
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000200008

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