Validation of sleep-staging accuracy for an in-home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apnea
Abstract Efforts to simplify standard polysomnography (PSG) in laboratories, especially for obstructive sleep apnea (OSA), and assess its agreement with portable electroencephalogram (EEG) devices are limited. We aimed to evaluate the agreement between a portable EEG device and type I PSG in patient...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-53827-1 |
| _version_ | 1797274620505620480 |
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| author | Jaehoon Seol Shigeru Chiba Fusae Kawana Saki Tsumoto Minori Masaki Morie Tominaga Takashi Amemiya Akihiro Tani Tetsuro Hiei Hiroyuki Yoshimine Hideaki Kondo Masashi Yanagisawa |
| author_facet | Jaehoon Seol Shigeru Chiba Fusae Kawana Saki Tsumoto Minori Masaki Morie Tominaga Takashi Amemiya Akihiro Tani Tetsuro Hiei Hiroyuki Yoshimine Hideaki Kondo Masashi Yanagisawa |
| author_sort | Jaehoon Seol |
| collection | DOAJ |
| description | Abstract Efforts to simplify standard polysomnography (PSG) in laboratories, especially for obstructive sleep apnea (OSA), and assess its agreement with portable electroencephalogram (EEG) devices are limited. We aimed to evaluate the agreement between a portable EEG device and type I PSG in patients with OSA and examine the EEG-based arousal index’s ability to estimate apnea severity. We enrolled 77 Japanese patients with OSA who underwent simultaneous type I PSG and portable EEG monitoring. Combining pulse rate, oxygen saturation (SpO2), and EEG improved sleep staging accuracy. Bland–Altman plots, paired t-tests, and receiver operating characteristics curves were used to assess agreement and screening accuracy. Significant small biases were observed for total sleep time, sleep latency, awakening after falling asleep, sleep efficiency, N1, N2, and N3 rates, arousal index, and apnea indexes. All variables showed > 95% agreement in the Bland–Altman analysis, with interclass correlation coefficients of 0.761–0.982, indicating high inter-instrument validity. The EEG-based arousal index demonstrated sufficient power for screening AHI ≥ 15 and ≥ 30 and yielded promising results in predicting apnea severity. Portable EEG device showed strong agreement with type I PSG in patients with OSA. These suggest that patients with OSA may assess their condition at home. |
| first_indexed | 2024-03-07T15:01:53Z |
| format | Article |
| id | doaj.art-eac44dae3aaa4c1b820a10186eac63f2 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-07T15:01:53Z |
| publishDate | 2024-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-eac44dae3aaa4c1b820a10186eac63f22024-03-05T19:09:06ZengNature PortfolioScientific Reports2045-23222024-02-0114111010.1038/s41598-024-53827-1Validation of sleep-staging accuracy for an in-home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apneaJaehoon Seol0Shigeru Chiba1Fusae Kawana2Saki Tsumoto3Minori Masaki4Morie Tominaga5Takashi Amemiya6Akihiro Tani7Tetsuro Hiei8Hiroyuki Yoshimine9Hideaki Kondo10Masashi Yanagisawa11Faculty of Health and Sports Sciences, University of TsukubaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaCardiovascular Respiratory Sleep Medicine, Juntendo University Graduate School of MedicineInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaS’UIMIN, Inc.S’UIMIN, Inc.S’UIMIN, Inc.S’UIMIN, Inc.Department of Respiratory Medicine, Inoue HospitalDepartment of General Medicine, Institute of Biomedical Sciences, Nagasaki UniversityInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaAbstract Efforts to simplify standard polysomnography (PSG) in laboratories, especially for obstructive sleep apnea (OSA), and assess its agreement with portable electroencephalogram (EEG) devices are limited. We aimed to evaluate the agreement between a portable EEG device and type I PSG in patients with OSA and examine the EEG-based arousal index’s ability to estimate apnea severity. We enrolled 77 Japanese patients with OSA who underwent simultaneous type I PSG and portable EEG monitoring. Combining pulse rate, oxygen saturation (SpO2), and EEG improved sleep staging accuracy. Bland–Altman plots, paired t-tests, and receiver operating characteristics curves were used to assess agreement and screening accuracy. Significant small biases were observed for total sleep time, sleep latency, awakening after falling asleep, sleep efficiency, N1, N2, and N3 rates, arousal index, and apnea indexes. All variables showed > 95% agreement in the Bland–Altman analysis, with interclass correlation coefficients of 0.761–0.982, indicating high inter-instrument validity. The EEG-based arousal index demonstrated sufficient power for screening AHI ≥ 15 and ≥ 30 and yielded promising results in predicting apnea severity. Portable EEG device showed strong agreement with type I PSG in patients with OSA. These suggest that patients with OSA may assess their condition at home.https://doi.org/10.1038/s41598-024-53827-1 |
| spellingShingle | Jaehoon Seol Shigeru Chiba Fusae Kawana Saki Tsumoto Minori Masaki Morie Tominaga Takashi Amemiya Akihiro Tani Tetsuro Hiei Hiroyuki Yoshimine Hideaki Kondo Masashi Yanagisawa Validation of sleep-staging accuracy for an in-home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apnea Scientific Reports |
| title | Validation of sleep-staging accuracy for an in-home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apnea |
| title_full | Validation of sleep-staging accuracy for an in-home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apnea |
| title_fullStr | Validation of sleep-staging accuracy for an in-home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apnea |
| title_full_unstemmed | Validation of sleep-staging accuracy for an in-home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apnea |
| title_short | Validation of sleep-staging accuracy for an in-home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apnea |
| title_sort | validation of sleep staging accuracy for an in home sleep electroencephalography device compared with simultaneous polysomnography in patients with obstructive sleep apnea |
| url | https://doi.org/10.1038/s41598-024-53827-1 |
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