The Association of Healthy Aging with Multimorbidity: IKARIA Study
The aim of this study was to evaluate several sociodemographic, lifestyle, and clinical characteristics of the IKARIA study participants and to find healthy aging trajectories of multimorbidity of Ikarian islanders. During 2009, 1410 people (aged 30+) from Ikaria Island, Greece, were voluntarily enr...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | Nutrients |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6643/13/4/1386 |
_version_ | 1797537019214168064 |
---|---|
author | Alexandra Foscolou Christina Chrysohoou Kyriakos Dimitriadis Konstantina Masoura Georgia Vogiatzi Viktor Gkotzamanis George Lazaros Costas Tsioufis Christodoulos Stefanadis |
author_facet | Alexandra Foscolou Christina Chrysohoou Kyriakos Dimitriadis Konstantina Masoura Georgia Vogiatzi Viktor Gkotzamanis George Lazaros Costas Tsioufis Christodoulos Stefanadis |
author_sort | Alexandra Foscolou |
collection | DOAJ |
description | The aim of this study was to evaluate several sociodemographic, lifestyle, and clinical characteristics of the IKARIA study participants and to find healthy aging trajectories of multimorbidity of Ikarian islanders. During 2009, 1410 people (aged 30+) from Ikaria Island, Greece, were voluntarily enrolled in the IKARIA study. Multimorbidity was defined as the combination of at least two of the following chronic diseases: hypertension; hypercholesterolemia; diabetes; obesity; cancer; CVD; osteoporosis; thyroid, renal, and chronic obstructive pulmonary disease. A healthy aging index (HAI) ranging from 0 to 100 was constructed using 4 attributes, i.e., depression symptomatology, cognitive function, mobility, and socializing. The prevalence of multimorbidity was 51% among men and 65.5% among women, while the average number of comorbidities was 1.7 ± 1.4 for men and 2.2 ± 1.4 for women. The most prevalent chronic diseases among men with multimorbidity were hypertension, hypercholesterolemia, and obesity while among women they were hypertension, hypercholesterolemia, and thyroid disease. Multimorbidity was correlated with HAI (Spearman’s rho = −0.127, <i>p</i> < 0.001) and for every 10-unit increase in HAI, participants had 20% lower odds of being multimorbid. Multimorbidity in relation to HAI revealed a different trend across aging among men and women, coinciding only in the seventh decade of life. Aging is usually accompanied by chronic diseases, but multimorbidity seems to also be common among younger adults. However, healthy aging is a lifelong process that may lead to limited co-morbidities across the lifespan. |
first_indexed | 2024-03-10T12:10:06Z |
format | Article |
id | doaj.art-eac615f80207426091eb0e3dcd3bcf67 |
institution | Directory Open Access Journal |
issn | 2072-6643 |
language | English |
last_indexed | 2024-03-10T12:10:06Z |
publishDate | 2021-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Nutrients |
spelling | doaj.art-eac615f80207426091eb0e3dcd3bcf672023-11-21T16:20:28ZengMDPI AGNutrients2072-66432021-04-01134138610.3390/nu13041386The Association of Healthy Aging with Multimorbidity: IKARIA StudyAlexandra Foscolou0Christina Chrysohoou1Kyriakos Dimitriadis2Konstantina Masoura3Georgia Vogiatzi4Viktor Gkotzamanis5George Lazaros6Costas Tsioufis7Christodoulos Stefanadis8First Cardiology Clinic, Hippokration Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, GreeceFirst Cardiology Clinic, Hippokration Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, GreeceFirst Cardiology Clinic, Hippokration Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, GreeceFirst Cardiology Clinic, Hippokration Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, GreeceFirst Cardiology Clinic, Hippokration Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, GreeceDepartment of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University of Athens, 17676 Athens, GreeceFirst Cardiology Clinic, Hippokration Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, GreeceFirst Cardiology Clinic, Hippokration Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, GreeceFirst Cardiology Clinic, Hippokration Hospital, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, GreeceThe aim of this study was to evaluate several sociodemographic, lifestyle, and clinical characteristics of the IKARIA study participants and to find healthy aging trajectories of multimorbidity of Ikarian islanders. During 2009, 1410 people (aged 30+) from Ikaria Island, Greece, were voluntarily enrolled in the IKARIA study. Multimorbidity was defined as the combination of at least two of the following chronic diseases: hypertension; hypercholesterolemia; diabetes; obesity; cancer; CVD; osteoporosis; thyroid, renal, and chronic obstructive pulmonary disease. A healthy aging index (HAI) ranging from 0 to 100 was constructed using 4 attributes, i.e., depression symptomatology, cognitive function, mobility, and socializing. The prevalence of multimorbidity was 51% among men and 65.5% among women, while the average number of comorbidities was 1.7 ± 1.4 for men and 2.2 ± 1.4 for women. The most prevalent chronic diseases among men with multimorbidity were hypertension, hypercholesterolemia, and obesity while among women they were hypertension, hypercholesterolemia, and thyroid disease. Multimorbidity was correlated with HAI (Spearman’s rho = −0.127, <i>p</i> < 0.001) and for every 10-unit increase in HAI, participants had 20% lower odds of being multimorbid. Multimorbidity in relation to HAI revealed a different trend across aging among men and women, coinciding only in the seventh decade of life. Aging is usually accompanied by chronic diseases, but multimorbidity seems to also be common among younger adults. However, healthy aging is a lifelong process that may lead to limited co-morbidities across the lifespan.https://www.mdpi.com/2072-6643/13/4/1386aginghealthy agingmultimorbiditychronic diseaseIkarialongevity |
spellingShingle | Alexandra Foscolou Christina Chrysohoou Kyriakos Dimitriadis Konstantina Masoura Georgia Vogiatzi Viktor Gkotzamanis George Lazaros Costas Tsioufis Christodoulos Stefanadis The Association of Healthy Aging with Multimorbidity: IKARIA Study Nutrients aging healthy aging multimorbidity chronic disease Ikaria longevity |
title | The Association of Healthy Aging with Multimorbidity: IKARIA Study |
title_full | The Association of Healthy Aging with Multimorbidity: IKARIA Study |
title_fullStr | The Association of Healthy Aging with Multimorbidity: IKARIA Study |
title_full_unstemmed | The Association of Healthy Aging with Multimorbidity: IKARIA Study |
title_short | The Association of Healthy Aging with Multimorbidity: IKARIA Study |
title_sort | association of healthy aging with multimorbidity ikaria study |
topic | aging healthy aging multimorbidity chronic disease Ikaria longevity |
url | https://www.mdpi.com/2072-6643/13/4/1386 |
work_keys_str_mv | AT alexandrafoscolou theassociationofhealthyagingwithmultimorbidityikariastudy AT christinachrysohoou theassociationofhealthyagingwithmultimorbidityikariastudy AT kyriakosdimitriadis theassociationofhealthyagingwithmultimorbidityikariastudy AT konstantinamasoura theassociationofhealthyagingwithmultimorbidityikariastudy AT georgiavogiatzi theassociationofhealthyagingwithmultimorbidityikariastudy AT viktorgkotzamanis theassociationofhealthyagingwithmultimorbidityikariastudy AT georgelazaros theassociationofhealthyagingwithmultimorbidityikariastudy AT costastsioufis theassociationofhealthyagingwithmultimorbidityikariastudy AT christodoulosstefanadis theassociationofhealthyagingwithmultimorbidityikariastudy AT alexandrafoscolou associationofhealthyagingwithmultimorbidityikariastudy AT christinachrysohoou associationofhealthyagingwithmultimorbidityikariastudy AT kyriakosdimitriadis associationofhealthyagingwithmultimorbidityikariastudy AT konstantinamasoura associationofhealthyagingwithmultimorbidityikariastudy AT georgiavogiatzi associationofhealthyagingwithmultimorbidityikariastudy AT viktorgkotzamanis associationofhealthyagingwithmultimorbidityikariastudy AT georgelazaros associationofhealthyagingwithmultimorbidityikariastudy AT costastsioufis associationofhealthyagingwithmultimorbidityikariastudy AT christodoulosstefanadis associationofhealthyagingwithmultimorbidityikariastudy |