Structure of human cytomegalovirus UL141 binding to TRAIL-R2 reveals novel, non-canonical death receptor interactions.

Structure of human cytomegalovirus UL141 binding to TRAIL-R2 reveals novel, non-canonical death receptor interactions.

The TRAIL (TNF-related apoptosis inducing ligand) death receptors (DRs) of the tumor necrosis factor receptor superfamily (TNFRSF) can promote apoptosis and regulate antiviral immunity by maintaining immune homeostasis during infection. In turn, human cytomegalovirus (HCMV) expresses immunomodulator...

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Bibliographic Details
Main Authors:	Ivana Nemčovičová, Chris A Benedict, Dirk M Zajonc
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-03-01
Series:	PLoS Pathogens
Online Access:	http://europepmc.org/articles/PMC3605307?pdf=render

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