Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation.
Presence of left atrial (LA) fibrosis reflects underlying atrial cardiomyopathy. Interatrial block (IAB) is associated with LA fibrosis in patients with atrial fibrillation (AF). The association of IAB and LA fibrosis in the patients without history of AF is unknown. We examined association of IAB a...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0297920&type=printable |
| _version_ | 1797304794637926400 |
|---|---|
| author | Arintaya Phrommintikul Natnicha Pongbangli Siriluck Gunaparn Narawudt Prasertwitayakij Teerapat Nantsupawat Wanwarang Wongcharoen |
| author_facet | Arintaya Phrommintikul Natnicha Pongbangli Siriluck Gunaparn Narawudt Prasertwitayakij Teerapat Nantsupawat Wanwarang Wongcharoen |
| author_sort | Arintaya Phrommintikul |
| collection | DOAJ |
| description | Presence of left atrial (LA) fibrosis reflects underlying atrial cardiomyopathy. Interatrial block (IAB) is associated with LA fibrosis in patients with atrial fibrillation (AF). The association of IAB and LA fibrosis in the patients without history of AF is unknown. We examined association of IAB and LA fibrosis in the patients without AF history. This is a retrospective analysis of 229 patients undergoing cardiac magnetic resonance imaging (CMR). LA fibrosis was reported from spatial extent of late gadolinium enhancement of CMR. IAB was measured from 12-lead electrocardiography using digital caliper. Of 229 patients undergoing CMR, prevalence of IAB was 50.2%. Patients with IAB were older (56.9±13.9 years vs. 45.9±19.2 years, p<0.001) and had higher prevalence of co-morbidities. Left ventricular ejection fraction was lower in IAB group. LA volume index (LAVI) was greater in IAB group (54.6±24.9 ml/m2 vs. 43.0±21.1 ml/m2, p<0.001). Patients with IAB had higher prevalence of LA fibrosis than those without IAB (70.4% vs. 21.2%; p<0.001). After multivariable analysis, only IAB and LAVI were independent factors that predict LA fibrosis. Prevalence of IAB in patients undergoing CMR was high. IAB was highly associated with LA fibrosis and larger LA size in patients without AF history. |
| first_indexed | 2024-03-08T00:15:38Z |
| format | Article |
| id | doaj.art-eace3cd31ff249fda7ccc732844d3222 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-03-08T00:15:38Z |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-eace3cd31ff249fda7ccc732844d32222024-02-17T05:33:03ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01192e029792010.1371/journal.pone.0297920Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation.Arintaya PhrommintikulNatnicha PongbangliSiriluck GunaparnNarawudt PrasertwitayakijTeerapat NantsupawatWanwarang WongcharoenPresence of left atrial (LA) fibrosis reflects underlying atrial cardiomyopathy. Interatrial block (IAB) is associated with LA fibrosis in patients with atrial fibrillation (AF). The association of IAB and LA fibrosis in the patients without history of AF is unknown. We examined association of IAB and LA fibrosis in the patients without AF history. This is a retrospective analysis of 229 patients undergoing cardiac magnetic resonance imaging (CMR). LA fibrosis was reported from spatial extent of late gadolinium enhancement of CMR. IAB was measured from 12-lead electrocardiography using digital caliper. Of 229 patients undergoing CMR, prevalence of IAB was 50.2%. Patients with IAB were older (56.9±13.9 years vs. 45.9±19.2 years, p<0.001) and had higher prevalence of co-morbidities. Left ventricular ejection fraction was lower in IAB group. LA volume index (LAVI) was greater in IAB group (54.6±24.9 ml/m2 vs. 43.0±21.1 ml/m2, p<0.001). Patients with IAB had higher prevalence of LA fibrosis than those without IAB (70.4% vs. 21.2%; p<0.001). After multivariable analysis, only IAB and LAVI were independent factors that predict LA fibrosis. Prevalence of IAB in patients undergoing CMR was high. IAB was highly associated with LA fibrosis and larger LA size in patients without AF history.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0297920&type=printable |
| spellingShingle | Arintaya Phrommintikul Natnicha Pongbangli Siriluck Gunaparn Narawudt Prasertwitayakij Teerapat Nantsupawat Wanwarang Wongcharoen Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation. PLoS ONE |
| title | Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation. |
| title_full | Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation. |
| title_fullStr | Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation. |
| title_full_unstemmed | Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation. |
| title_short | Association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation. |
| title_sort | association of the interatrial block and left atrial fibrosis in the patients without history of atrial fibrillation |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0297920&type=printable |
| work_keys_str_mv | AT arintayaphrommintikul associationoftheinteratrialblockandleftatrialfibrosisinthepatientswithouthistoryofatrialfibrillation AT natnichapongbangli associationoftheinteratrialblockandleftatrialfibrosisinthepatientswithouthistoryofatrialfibrillation AT siriluckgunaparn associationoftheinteratrialblockandleftatrialfibrosisinthepatientswithouthistoryofatrialfibrillation AT narawudtprasertwitayakij associationoftheinteratrialblockandleftatrialfibrosisinthepatientswithouthistoryofatrialfibrillation AT teerapatnantsupawat associationoftheinteratrialblockandleftatrialfibrosisinthepatientswithouthistoryofatrialfibrillation AT wanwarangwongcharoen associationoftheinteratrialblockandleftatrialfibrosisinthepatientswithouthistoryofatrialfibrillation |