Systematic Comparison of Beetle Luciferase-Luciferin Pairs as Sources of Near-Infrared Light for In Vitro and In Vivo Applications

Systematic Comparison of Beetle Luciferase-Luciferin Pairs as Sources of Near-Infrared Light for In Vitro and In Vivo Applications

Luciferases catalyze light-emitting reactions that produce a rainbow of colors from their substrates (luciferins), molecular oxygen, and often additional cofactors. These bioluminescence (BL) systems have afforded an incredible variety of basic research and medical applications. Driven by the import...

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Bibliographic Details
Main Authors: Bruce R. Branchini, Danielle M. Fontaine, Dawn Kohrt, Brian P. Huta, Allison R. Racela, Benjamin R. Fort, Tara L. Southworth, Aldo Roda
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
bioluminescence
firefly
near-infrared
HEK293T
biomarker
imaging
Online Access:https://www.mdpi.com/1422-0067/23/5/2451

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