Prostaglandin E<sub>2 </sub>receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein

Prostaglandin E<sub>2 </sub>receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein

<p>Abstract</p> <p>Background</p> <p>The pathogenesis of idiopathic Parkinson's disease (PD) remains elusive, although evidence has suggested that neuroinflammation characterized by activation of resident microglia in the brain may contribute significantly to neuro...

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Bibliographic Details
Main Authors: Schantz Aimee M, Davis Jeanne, Wang Yan, Liu Jun, Shie Feng-Shiun, Jin Jinghua, Montine Kathleen S, Montine Thomas J, Zhang Jing
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/4/1/2

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